Quinto, llorenç;
Aponte, joão J;
Menéndez, clara;
Sacarlal, jahit;
Assessor, pedro;
Espasa, mateus;
Mandomando, inácio;
Guinovart, caterina;
Macete, Eusébio;
Hirt, rosmarie;
Urassa, honorathy;
Navia, margarita M;
Alonso, pedro L;
Thompson, ricardo.
Introduction: Anaemia is the most frequent haematological disorder in childhood. The notion that defines naemia does not change throughout life, although parameters used for its evaluation show significant variations during childhood. Haematocrit (Hct) (%) is usually defined as three times the value of h...
Objective: To estimate the community incidence-rates of respiratory infections among infants in Manhiça, southern Mozambique, and to determine risk factors associated with these infections.
Methods: A cohort of children <1 year of age were visited at home every week until they turned one. During the vis...
Valles, Xavier;
Flannery, Brendan;
Roca, Anna;
Mandomando, Inacio;
Sigauque, Betuel;
Sanz, Sergi;
Schuchat, Anne;
Levine, Myron;
Soriano-Gabarro, Montserrat;
Alonso, Pedro.
Objective: To describe and compare serotype distribution and antibiotic susceptibility of invasive and nasopharyngeal isolates of Streptococcus pneumoniae from children in rural Mozambique. Methods: From August 2002 to July 2003, we prospectively obtained invasive pneumococcal isolates from children <15 ...
Roca, A;
Sigaúque, B;
Quintó, Ll;
Mandomando, L;
Vallès, X;
Espasa, M;
Abacassamo, F;
Sacarlal, J;
Macete, E;
Nhacolo, A;
Levine, M;
Alonso, P.
Objectivos Estimar a incidência e as características epidemiológicas do pneumococo invasivodoença (DPI) em crianças de <5 anos de idade residentes em uma área rural do sul de Moçambique.Métodos Como parte do manejo clínico de crianças internadas em Manhiçum Hospital Distrital,A vigilância pr...
Meningitis, Pneumococcal,
Meningitis, Pneumococcal/epidemiology,
Chloramphenicol/therapeutic use,
Rural Population,
Mozambique/epidemiology,
Population Surveillance/methods,
Pneumococcal Infections/epidemiology,
Pneumonia/chemically induced,
Rural Health,
Anti-Infective Agents/therapeutic use
Clara, menndez;
Romagosa, cleofe;
Ismail, mamudo R;
Carrilho, carla;
Saute, francisco;
Machungo, fernanda;
Osman, nafissa;
Bardaji, azucena;
Quinto, llorenc;
Dobano, carlota;
Naniche, denise;
Mayor, alfredo;
Alonso, pedro L;
Ordi, jaume.
Background: Maternal mortality is a major health problem concentrated in resource-poor regions. Accurate data on its causes using rigorous methods is lacking, but is essential to guide policy-makers and health professionals to reduce this intolerable burden. The aim of this study was to accurately descri...
Alonso, pedro L;
Sacarlal, jahit;
Aponte, john J;
Leach, amanda;
Macete, eusebio;
Milman, jessica;
Mandomando, inacio;
Spiessens, Bart;
Guinovart, caterina;
Espasa, mateu;
Bassat, quique;
Aide, pedro;
Anyinam, opokua Ofori;
Navia, margarita M;
Corachan, sabine.
Background: Development of an effective malaria vaccine could greatly contribute to disease control. RTS,S/AS02A is a pre-erythrocytic vaccine candidate based on Plasmodium falciparum circumsporozoite surface antigen. We aimed to assess vaccine efficacy, immunogenicity, and safety in young African childr...
We estimated the incidence of clinical malaria episodes by weekly home-based active case detection between December 1996 and July 1999 in 2 groups of children in Manhiça district in southern Mozambique. Cohort 1 comprised a random sample of children aged <10 years at recruitment and cohort 2 comprised n...
A total of 2057 children aged <10 years were selected at random from a demographic surveillance system and enrolled in 4 malariometric cross-sectional surveys in different seasons in Manhiça district in southern Mozambique. Plasmodium falciparum accounted for 90% of all malaria infections and the preval...
We describe the frequency of Plasmodium falciparum clones infecting individuals living in a rural area of southern Mozambique and analyse the relationship between multiplicity of infection, age and other malariometric indices, including prospective risk of clinical malaria. The genotyping was based on th...
Falciparum malaria affects pregnant women, especially primigravidae, but before malaria control programmes targeted to them can be designed, a description of the frequency and parity pattern of the infection is needed. There is little information on the frequency and effect of submicroscopic malaria infe...
Malaria, Falciparum/complications,
Malaria, Falciparum/epidemiology,
Plasmodium falciparum/isolation & purification,
Pregnancy Complications, Parasitic/epidemiology,
Mozambique/epidemiology,
Malaria, Falciparum/prevention & control,
Morbidity/trends
