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Effect of point-of-care CD4 cell count tests on retention of patients and rates of antiretroviral therapy initiation in primary health clinics: an observational cohort study

Jani, lesh V; Sitoe, Nádia E; Alfai, Eunice R; Chongo, Patrina L; Quevedo, Jorge I; Rocha, Beatriz M; Lehe, Jonathan D; Peter, Trevor F.
Lancet; 378 (9802), 2011
Background: Loss to follow-up of HIV-positive patients before initiation of antiretroviral therapy can exceed 50% in low-income settings and is a challenge to the scale-up of treatment. We implemented point-of-care counting of CD4 cells in Mozambique and assessed the effect on loss to follow-up before im...
Age Factors, Ambulatory Care, Attitude to Health, CD4 Lymphocyte Count, Cohort Studies, Confidence Intervals, Developing Countries, Treatment Outcome, Patient Compliance, Mozambique, Retrospective Studies, Socioeconomic Factors
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AAge interactions in the development of naturally acquired immunity to plasmodium falciparum and its clinical presentation

Aponte, John J; Menendez, Clara; Schellenberg, David; Kahigwa, Elizeus; Mshinda, Hassan; Vountasou, Penelope; Tanner, Marcel; Alonso, Pedro L.
PloS med; 4 (7), 2007
Background Naturally acquired malaria immunity has many determinants and, in the absence of immunological markers of protection, studies assessing malaria incidence through clinical endpoints remain an approach to defining immunity acquisition. We investigated the role of age in disease incidence and th...
Age Factors, Anemia, Antigens, Protozoan/immunology, Anemia/prevention & control, Anemia/immunology, Dapsone/therapeutic use, Drug Therapy, Combination, Malaria, Falciparum/immunology, Malaria, Falciparum/prevention & control, Malaria, Falciparum/epidemiology, Plasmodium falciparum/immunology, Plasmodium falciparum/drug effects, Tanzania/epidemiology, Pyrimethamine/therapeutic use, Treatment Outcome
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