Background: Malaria is the leading cause of death among children in Mozambique. Prevalence and factors associated with malaria are not well studied among children in rural Zambézia Province. Whether prevalence of malaria varies across diverse districts within the province is unknown. Methods: A cross...
Mozambique/epidemiology,
Diagnosis,
Education,
Socioeconomic Factors,
Malaria/epidemiology,
Prevalence,
Logistic Models,
Methods,
Blood,
Diagnostic Tests, Routine,
Fever,
Beds,
Cross-Sectional Studies
After the decrease in clinical malaria incidence observed in Mozambique until 2009, a steady resurgence of cases per year has been reported nationally, reaching alarming levels in 2014. However, little is known about the clinical profile of the cases presented, or the possible epidemiological factors con...
Gudo, Eduardo Samo;
Lesko, Birgitta;
Vene, Sirkka;
Lagerqvist, Nina;
Candido, Sandra Isabel;
Deus, Nilsa Razão de;
Pinto, Félix Dinis;
Pinto, Gabriela;
Monteiro, Vanessa;
Evaristo, Virginia Lara;
Bhatt, Nilesh;
Manhica, Ivan;
Falk, Kerstin I.
In sub-Saharan Africa, febrile patients are often assumed to have, and are treated for, malaria, but when tested, many are malaria-negative. Because emerging diseases, such as chikungunya virus (CHIKV) and dengue virus (DENV) infections, cause outbreaks around the world (1–3), the importance of these p...
Since the first reported epidemic of dengue in Pemba, the capital of Cabo Delgado province, in 1984-1985, no further cases have been reported in Mozambique. In March 2014, the Provincial Health Directorate of Cabo Delgado reported a suspected dengue outbreak in Pemba, associated with a recent increase in...
Madrid, Lola;
Acácio, Sozinho;
Nhampossa, Tácita;
Lanaspa, Miguel;
Sitoe, Antonio;
Maculuve, Sónia Amós;
Mucavele, Helio;
Quinto, Lourenço;
Sigauque, Betuel;
Bassat, Quique.
Abstract. Hypoglycemia is a life-threatening complication of several diseases in childhood. We describe the prevalence and incidence of hypoglycemia among admitted Mozambican children, establishing its associated risk factors. We retro spectively reviewed clinical data of 13 years collected through an on...
Mayor, Alfredo;
Bardají, Azucena;
Macete, Eusebio;
Nhampossa, Tacilta;
Fonseca, Ana Maria;
González, Raquel;
Maculuve, Sonia;
Cisteró, Pau;
Rupérez, Maria;
Campo, Joe;
Vala, Anifa;
Sigaúque, Betuel;
Jiménez, Alfons;
Machevo, Sonia;
Fuente, Laura de la;
Nhama, Abel;
Luis, Leopoldina;
Aponte, John J;
Acácio, Sozinho;
Nhacolo, Arsenio;
Chitnis, Chetan;
Dobaño, Carlota;
Sevene, Esperanza;
Alonso, Pedro Luis;
Menéndez, Clara.
Background: Prevention of reinfection and resurgence is an integral component of the goal to eradicate malaria. However, the adverse effects of malaria resurgences are not known.
Methods: We assessed the prevalence of Plasmodium falciparum infection among 1819 Mozambican women who delivered infants betwe...
Antibodies, Protozoan/blood,
Immunoglobulin G/blood,
Malaria, Falciparum/classification,
Malaria, Falciparum/epidemiology,
Malaria, Falciparum/immunology,
Mozambique/epidemiology,
Parasite Load,
Parity,
Plasmodium falciparum/immunology,
Plasmodium falciparum/isolation & purification,
Pregnancy Complications, Infectious/classification,
Pregnancy Complications, Infectious/epidemiology,
Pregnancy Complications, Infectious/immunology,
Severity of Illness Index
Glunt, katey d;
Abílio, ana paula;
Bassat, quique;
Bulo, helder;
Gilbert, allison e;
Huijben, silvie;
Manaca, maria nélia;
Macete, eusebio;
Alonso, pedro;
Paaijmans, krijin p.
Background: Chemical insecticides are crucial to malaria control and elimination programmes. The frontline vector control interventions depend mainly on pyrethroids; all long-lasting insecticidal nets (LLINs) and more than 80% of indoor residual spraying (IRS) campaigns use chemicals from this class. Thi...
Anopheles/drug effects,
Insect Vectors/drug effects,
Insecticide Resistance,
Insecticide-Treated Bednets,
Insecticides/pharmacology,
Insecticides/therapeutic use,
Malaria/transmission,
Mosquito Control,
Pyrethrins/pharmacology,
Pyrethrins/therapeutic use,
Mozambique/epidemiology
Background: Current World Health Organization and national protocols recommend the ‘test and treat’ strategy for the management of uncomplicated malaria, to reduce over prescription of artemisinin-based combination treatment (ACT). Therefore, adherence to these protocols varies in different sub-Sahar...
Mozambique/epidemiology,
Prescription Drug Overuse/mortality,
Prescriptions,
Medical Records,
Organization and Administration,
Malaria/epidemiology,
Patients,
Malaria/prevention & control,
29161,
Laboratories/statistics & numerical data,
World Health Organization,
35170/methods,
Malaria/blood,
Public Health,
Therapeutics/adverse effects
González, Raquel;
Desai, Meghna;
Macete 3, Eusebio;
Ouma, Peter;
Kakolwa, Mwaka A;
Abdulla, Salim;
Aponte, John J;
Bulo, Helder;
Kabanywanyi, Abdunoor M;
Katana, Abraham;
Maculuve, Sonia;
Mayor, Alfredo;
Nhacolo, Arsenio;
Otieno, Kephas;
Pahlavan, Golbahar;
Rupérez, María;
Sevene, Esperança;
Slutsker, Laurence;
Vala, Anifa;
Williamsom, John;
Menéndez, Clara.
Background: Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended for malaria prevention in HIV-negative pregnant women, but it is contraindicated in HIV-infected women taking daily cotrimoxazole prophylaxis (CTXp) because of potential added risk of adve...
Antimalarials/administration & dosage,
Double-Blind Method,
Follow-Up Studies,
HIV Infections/diagnosis,
HIV Infections/drug therapy,
HIV Infections/epidemiology,
Infectious Disease Transmission, Vertical/prevention & control,
Malaria/diagnosis,
Malaria/epidemiology,
Malaria/prevention & control,
Mefloquine/administration & dosage,
Pregnancy Complications, Infectious/diagnosis,
Pregnancy Complications, Infectious/epidemiology,
Pregnancy Complications, Infectious/prevention & control,
Pregnancy Complications, Parasitic/diagnosis,
Pregnancy Complications, Parasitic/epidemiology,
Pregnancy Complications, Parasitic/prevention & control,
Pregnancy Outcome,
Mozambique/epidemiology,
Tanzania/epidemiology,
Kenya/epidemiology,
Trimethoprim, Sulfamethoxazole Drug Combination/administration & dosage
Hyle, emily, p;
Jani, ilesh, v;
Lehe, jonathan;
Su, amanda, e;
Wood, robin;
Quevedo, jorge;
Losina, elena;
Bassett, ingrid, v;
Pei, pamela, p;
Paltiel, a, david;
Resch, stephen;
Freedberg, kenneth, a;
Peter, trevor;
Walensky, rochelle, p.
Background: Point-of-care CD4 tests at HIV diagnosis could improve linkage to care in resource-limited settings. Our objective is to evaluate the clinical and economic impact of point-of-care CD4 tests compared to laboratory-based tests in Mozambique.
Methods and findings: We use a validated model of HIV...
CD4 Lymphocyte Count/economics,
CD4 Lymphocyte Count/methods,
Cost-Benefit Analysis/economics,
Cost-Benefit Analysis/methods,
HIV Infections/diagnosis,
HIV Infections/epidemiology,
HIV Infections/economics,
Health Care Costs,
Health Resources/economics,
Mozambique/epidemiology,
Point-of-Care Systems/economics
