Arnaldo , Paulo;
Vallbona, Eduard Rovira;
Langa, Jerónimo S;
Salvador, Crizolgo;
Guetens, Pieter;
Chiheb, Driss;
Xavier , Bernardete;
Kestens, Luc;
Enosse, Sónia M;
Urgell , Anna Rosanas.
Malaria in pregnancy leads to serious adverse effects on the mother and the child and accounts for 75,000-200,000 infant deaths every year. Currently, the World Health Organization recommends intermittent preventive treatment of malaria in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) at each sche...
Pyrimethamine/administration & dosage,
Sulfadoxine/administration & dosage,
Antimalarials/therapeutic use,
d0082880,
d0149300,
d0149440,
d0090350,
Antimalarials/administration & dosage,
Pharmaceutical Preparations,
Health Facilities,
Drug Combinations,
Labor, Obstetric/radiation effects,
Pregnancy Complications, Parasitic,
Mozambique,
Risk Factors,
Malaria/prevention & control
Background: Malaria is the leading cause of death among children in Mozambique. Prevalence and factors associated with malaria are not well studied among children in rural Zambézia Province. Whether prevalence of malaria varies across diverse districts within the province is unknown. Methods: A cross...
Mozambique/epidemiology,
Diagnosis,
Education,
Socioeconomic Factors,
Malaria/epidemiology,
Prevalence,
Logistic Models,
Methods,
Blood,
Diagnostic Tests, Routine,
Fever,
Beds,
Cross-Sectional Studies
While long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) are the cornerstones of malaria vector control throughout sub-Saharan Africa, there is an urgent need for the development of novel insecticide delivery mechanisms to sustain and consolidate gains in disease reduction and to t...
Raquel Gonzalez and colleagues highlight an urgent need to evaluate antimalarials that can be safely administered to HIV-infected pregnant women on antiretroviral treatment and cotrimoxazole prophylaxis.
African HIV-infected pregnant women are the most vulnerable population group to
malaria infection.
...
Adjei, aexander;
Bana, solomon narh;
Amu, alberta;
Kukula, vida;
Nagai, richard afedi;
Agyei, seth owusu;
Oduro, abraham;
Macete, Eusebio;
Abdulla, salim;
Halidou, tinto;
Sie, ali;
Osei, isaac;
Sevene, esperance;
Asante, kwaku-poku;
Mulokozi, abdunoor;
Compaore, guillaume;
Valea, innocent;
Adjuik, martin;
Baiden, rita;
Ogutu, Bernhards;
Binka, fred;
Gyapong, margaret.
Background: Dihydroartemisinin-piperaquine (DHA-PQ) is one of five WHO recommended artemisinin combination therapy (ACT) for the treatment of uncomplicated malaria. However, little was known on its post-registration safety and effectiveness in sub-Saharan Africa. DHA-PQ provides a long post-treatment pro...
Balabanidou, Vasileia;
Kampouraki, Anastasia;
Maclean, Marina;
Blomquist, Gary;
Tittiger, Claus;
Juarez, Marta Patricia;
Javier Mijailovsky, Sergio;
Chalepakis, George;
Anthousi, Amalia;
Lynd, Amy;
Sanou, Antoine;
Hemingway, Janet;
Ranson, Hilary;
Lycett, Gareth;
Vontas, John.
The role of cuticle changes in insecticide resistance in the major malariavector Anopheles gambiae was assessed. The rate of internalization of14C deltamethrin was significantly slower in a resistant strain than in asusceptible strain. Topical application of an acetone insecticide formu-lation to circumv...
Plucinski, m m;
Chicuecue, s;
Macete, e;
Chambe, g a;
Muguande, o;
Matsinhe, g;
Colborn, j;
Yoon, s s;
Doyle, t j;
Kachur, s p;
Aide, p;
Alonso, p l;
Guinovart, c;
Morgan, j.
Objective: Universal coverage with insecticide-treated bed nets is a cornerstone of modern malaria control. Mozambique has developed a novel bed net allocation strategy, where the number of bed nets allocated per household is calculated on the basis of household composition and assumptions about who slee...
Glunt, katey d;
Abílio, ana paula;
Bassat, quique;
Bulo, helder;
Gilbert, allison e;
Huijben, silvie;
Manaca, maria nélia;
Macete, eusebio;
Alonso, pedro;
Paaijmans, krijin p.
Background: Chemical insecticides are crucial to malaria control and elimination programmes. The frontline vector control interventions depend mainly on pyrethroids; all long-lasting insecticidal nets (LLINs) and more than 80% of indoor residual spraying (IRS) campaigns use chemicals from this class. Thi...
Anopheles/drug effects,
Insect Vectors/drug effects,
Insecticide Resistance,
Insecticide-Treated Bednets,
Insecticides/pharmacology,
Insecticides/therapeutic use,
Malaria/transmission,
Mosquito Control,
Pyrethrins/pharmacology,
Pyrethrins/therapeutic use,
Mozambique/epidemiology
Background: Current World Health Organization and national protocols recommend the ‘test and treat’ strategy for the management of uncomplicated malaria, to reduce over prescription of artemisinin-based combination treatment (ACT). Therefore, adherence to these protocols varies in different sub-Sahar...
Mozambique/epidemiology,
Prescription Drug Overuse/mortality,
Prescriptions,
Medical Records,
Organization and Administration,
Malaria/epidemiology,
Patients,
Malaria/prevention & control,
29161,
Laboratories/statistics & numerical data,
World Health Organization,
35170/methods,
Malaria/blood,
Public Health,
Therapeutics/adverse effects
González, raquel;
Ngoma, ghyslain mombo;
Ouédraogo, smaïla;
Kakolwa, mwaka a;
Abdulla, salim;
Accrombessi, manfred;
Aponte, john j;
Diop, daisy akerey;
Basra, arti;
Briand, valérie;
Capan, meskure;
Cot , michel;
Kabanywanyi, abdunoor m;
Kleine, christian;
Kremsner, peter g;
Macete, eusebio;
Mackanga, jean-rodolphe;
Massougbodgi, achille;
Mayor, alfredo;
Nhacolo, arsenio;
Pahlavan, golbahar;
Ramharter, michael;
Rupérez, maría;
Sevene, esperança;
Vala, anifa;
Manego, rella zoleko;
Menéndez, clara.
Background: Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended by WHO to prevent malaria in African pregnant women. The spread of SP parasite resistance has raised concerns regarding long-term use for IPT. Mefloquine (MQ) is the most promising of avai...
Africa South of the Sahara/epidemiology,
Antimalarials/administration & dosage,
Cohort Studies,
HIV Infections,
Infant, Low Birth Weight,
Insecticide-Treated Bednets/statistics & numerical data,
Malaria/diagnosis,
Malaria/epidemiology,
Malaria/prevention & control,
Mefloquine/administration & dosage,
Pregnancy Complications, Parasitic/diagnosis,
Pregnancy Complications, Parasitic/epidemiology,
Pregnancy Complications, Parasitic/prevention & control,
Preventive Health Services/statistics & numerical data,
Treatment Outcome,
Mozambique
