AIM

Changing Trends in P. falciparum Burden, Immunity, and Disease in Pregnancy

N. Engl. j. med; (), 2015

Background: Prevention of reinfection and resurgence is an integral component of the goal to eradicate malaria. However, the adverse effects of malaria resurgences are not known. Methods: We assessed the prevalence of Plasmodium falciparum infection among 1819 Mozambican women who delivered infants betwe...

Antibodies, Protozoan/blood, Immunoglobulin G/blood, Malaria, Falciparum/classification, Malaria, Falciparum/epidemiology, Malaria, Falciparum/immunology, Mozambique/epidemiology, Parasite Load, Parity, Plasmodium falciparum/immunology, Plasmodium falciparum/isolation & purification, Pregnancy Complications, Infectious/classification, Pregnancy Complications, Infectious/epidemiology, Pregnancy Complications, Infectious/immunology, Severity of Illness Index

Fulltext

Safety of the RTS, S/AS02D candidate malaria vaccine in infants living in a highly endemic area of Mozambique: a double blind randomised controlled phase I/IIb trial

Lancet; 370 (9598), 2007

Background: Malaria remains a leading global health problem that requires the improved use of existing interventions and the accelerated development of new control methods. We aimed to assess the safety, immunogenicity, and initial efficacy of the malaria vaccine RTS,S/AS02D in infants in Africa. Methods...