AIM

Therapeutic potential of concurrent administration of Hippocratea africana and Eremomastax speciosa in the treatment of Plasmodium berghei infected mice

Anthony Uwah, F; Blessing Effiong, O; Jackson Obot, S; Idongesit Obioku, J; Alphonsus Udoh, E.

Ibom Medical Journal; 15 (2), 2022

Context: Despite the commonness of polyherbal therapy among the locals in the treatment of malaria in Nigeria, there are no adequate data on the therapeutic potentials and safety profile of these herbal combinations. The use of these plants in combination in the treatment of suspected and confirmed malar...

Hippocrateaceae, Malaria, Phytotherapy, Apocynaceae, Mice, Therapeutics

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Anticonvulsant Activity of Carissa carandas Linn. Root Extract in Experimental Mice

Karunakar, Hegde; Thakker, Shalin P; Joshi, Arun B; Shastry, C S; Chandrashekhar, K S.

Trop. j. pharm. res. (Online); 8 (2), 2009

Purpose: The aim of the present study was to investigate anticonvulsant effect of the ethanolic extract of the roots of Carissa carandas (ERCC) on electrically and chemically induced seizures. Methods: The ethanolic extract of the roots of C. carandas (100, 200 and 400 mg/kg, i.p.) was studied for it...

Ethanol, Cell Extracts, Apocynaceae, Anticonvulsants, Seizures, Pentylenetetrazole, Picrotoxin

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In vitro anti-leishmanial and anti-tumour activities of a pentacyclic triterpenoid compound isolated from the fruits of Dregea volubilis Benth Asclepiadaceae

Biswas, Moulisha; Mandal Nirup, Bikash; Palit, Partha; Ghosh Ashoke, Kumar; Bannerjee, Sukdeb; Haldar Pallab, Kanti.

Trop. j. pharm. res. (Online); 8 (2), 2009

Purpose: Dregea volubilis Benth, commonly known as Jukti in Bengal, is used in the treatment of boils and abscesses from ancient times. The purpose of this study is to elucidate the active compounds and as well as their anti-leishmanial and anti-tumour activities. Methods: Dried and crushed fruits of Dre...

Pentacyclic Triterpenes, Spectrum Analysis, Triterpenes, Apocynaceae, Petroleum

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