In sub-Saharan Africa, recent data about causes of adult death and care-seeking during illnesses are limited. This analysis examines adult deaths using verbal and social autopsy data from a nationally and provincially representative sample registration system in Mozambique. Causes of death among those 18...
Fiksel, Jacob;
Gilbert, Brian;
Wilson, Emily;
Valter, Henry;
Kante, Almamy;
Akum, Aveika;
Blau, Dianna;
Bassat, Quique;
Macicame, Ivalda;
Samo Gudo, Eduardo;
Black, Robert;
Zeger, Scott;
Amouzou, Agbessi;
Datta, Abhirup.
Verbal autopsies (VAs) are extensively used to determine cause of death (COD) in many low- and middle-income countries. However, COD determination from VA can be inaccurate. Computer coded verbal autopsy (CCVA) algorithms used for this task are imperfect and misclassify COD for a large proportion of deat...
Gilbert, Brian;
Fiksel, Jacob;
Wilson, Emily;
Kalter, Henry;
Kante, Almamy;
Akum, Aveika;
Blau, Dianna;
Bassat, Quique;
Macicame, Ivalda;
Gudo, Eduardo Samo;
Black, Robert;
Zeger, Scott;
Amouzou, Agbessi;
Datta, Abhirup.
The Countrywide Mortality Surveillance for Action platform is collecting verbal autopsy (VA) records from a nationally representative sample in Mozambique. These records are used to estimate the national and subnational cause-specific mortality fractions (CSMFs) for children (1-59 months) and neonates (1...
The anatomical pathology autopsy serves several purposes, notably as a quality management tool for evaluation of accuracy in clinical diagnosis. Despite its value, for various reasons there has been an international decline in autopsies conducted. In the modern medical era, with all its advances in techn...
Background: Formalin-fixed paraffin-embedded (FFPE) tissue archives in hospitals, biobanks, and others offer a vast collection of extensive, readily available specimens for molecular testing. Unfortunately, the use of tissue samples for molecular diagnostic applications is challenging; thus, the forensic...
Autopsy,
DNA,
Paraffin,
Pain Measurement,
Archives,
Tissues,
Resolutions,
Molecular Docking Simulation,
Pathology, Molecular,
Polymerase Chain Reaction,
Genetic Testing
Asumanu, Edward;
Servor, Raymond X;
Laryea, Clement;
McAddy, Mary;
Hobenu, Fred;
Factchu, Raymond;
Agyemang-Bediako, Kwesi;
Nyarko, Edward O;
Nyarko, Godwin K;
Moroti, Marcus K;
Edusei, Lawrence.
Background: Causes of death during the coronavirus disease 2019 (COVID-19) pandemic ranhttp://crossmark.crossref.org/dialog/?doi=10.4102/ajlm.v11i1.1766=pdf&date_stamp=2022-11-23ge from direct consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to deaths unrelated to SA...
Severe acute respiratory syndrome–coronavirus-2 (SARS-CoV-2) enters cells using the angiotensin converting enzyme 2 (ACE2), which are expressed by the respiratory tract endothelium, epithelial cells of the stomach, duodenum, ileum, rectum, cholangiocytes, and hepatocytes. Pathological examinations of t...
Menendez, Clara;
Castillo, Paola;
Martinez, Miguel;
Jordao, Dercio;
Lovane, Lucilia;
Ismael, Mamudo R;
Carrilho, Carla;
Lorenzoni, Cesaltina;
Fernandes, Fabiola;
Nhampossa, Tacilta 2 8;
Hurtado, Juan Carlos;
Navarro, Mireia;
Casas, Isaac;
Ritchie, Paula Santos;
Bandeira, Sonia;
Mucumbi, Sibone;
Jaze, Zara;
Mabota, Flora;
Munguambe, Khátia;
Maixenchs, Maria;
Sanz, Ariadna;
Mandomando, Inacio;
Nadal, Alfons;
Gonce, Anna;
Almagro, Carmen Muñoz;
Quinto, Llorenç;
Vila, Jordi;
Macete, Eusebio;
Alonso, Pedro;
Ordi, Jaume;
Bassat, Quique.
Over 5 million stillbirths and neonatal deaths occur annually. Limited and imprecise information on the cause of these deaths hampers progress in achieving global health targets. Complete diagnostic autopsies (CDAs)-the gold standard for cause of death determination-are difficult to perform in most high-...
Bassat, Quique;
Castillo, Paola;
Martínez, miguel, j;
Jordao, dercio;
Lucilia, lovane;
Hurtado, juan carlos;
Nhampossa, tacilta;
Ritchie, paula, santos;
Bandeira, sónia;
Sambo, Calvino;
Chicamba, valeria;
Ismail, mamudo, r;
Carrilho, carla;
Lorenzoni, cesaltina;
Fernandes, fabiola;
Cisteró, Pau;
Mayor, alfredo;
Cossa, Anelsio;
Mandomando, inacio;
Navarro, mireia;
Casas, isaac;
Vila, jordi;
Munguambe, khátia;
Maixenchs, maria;
Sanz, ariadna;
Quintó, llorenç;
Macete, eusebio;
Alonso, pedro;
Menéndez, clara;
Ordi, jaume.
Background: In recent decades, the world has witnessed unprecedented progress in child survival. However, our knowledge of what is killing nearly 6 million children annually in low- and middle-income countries remains poor, partly because of the inadequacy and reduced precision of the methods currently u...
Castillo, Paola;
Martinez, Miguel J;
Ussene, Esperança;
Jordao, Dercio;
Lovane, Luciliao;
Ismail, Mamudo R;
Carrilho, Carla;
Lorenzoni, Cesaltina;
Fernandes, Fabiola;
Bene, Rosa;
Palhares, Antonio;
Ferreira, Luiz;
Mandomando, Inacio;
Vila, Jordi;
Hurtado, Juan Carlos;
Munguambe, Khátia;
Maixenchs, Maria;
Sanz, Ariadna;
Quinto, Llorenç;
Macete, Eusebio;
Alonso, Pedro;
Bassat, Quique;
Menendez, lara;
Ordi, Jaume.
There is an urgent need to identify tools able to provide reliable information on the cause of death in low-income regions, since current methods (verbal autopsy, clinical records, and complete autopsies) are either inaccurate, not feasible, or poorly accepted. We aimed to compare the performance of a st...
