Results: 7

Acute malnutrition in rural twins before their second birthday: insights from a cohort study in Burkina Faso

Background: Twins constitute a vulnerable subpopulation among children under 5 years of age. In sub-Saharan Africa, it has been found that multiple births tend to be undernourished and the risks of acute malnutrition and stunting are high.Objective: Examining the relationship between acute malnutrition a...

Epidemiology and surgical outcomes of primary brain tumours managed at a Tertiary Hospital in Arusha, Tanzania

Introduction: The epidemiology and outcome of brain tumours varies globally. We aimed to analyze the epidemiology and postsurgical outcomes of intracranial tumours in our setting. Methods: This is a retrospective cohort study. Data were obtained from patient clinical records between 2019 and 2020. Sub-gr...

Asymptomatic testing people for SARS-CoV-2 in healthcare facilities: A systematic review

Background: Asymptomatic testing involves the process whereby individuals who do not show symptoms of COVID-19 are tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection using any of the available laboratory test techniques. Aim: To evaluate the effectiveness of testing asympto...

Immediate and early engagement of same-day antiretroviral therapy initiation among newly diagnosed people living with HIV in urban Zambia: a retrospective cohort study

PAMJ One Health; 10 (4), 2023
Introduction: as Zambia moves towards attaining human immunodeficiency virus (HIV) epidemic control, it is clear significant efforts are required to facilitate achievement of UNAIDS treatment targets by 2030. To accelerate progress towards global target of 95% of people living with HIV (PLHIV) knowing th...

Tuberculosis treatment and factors associated with unsuccessful tuberculosis treatment outcome among TB/HIV co-infected patients in Rwanda: A retrospective cohort study

Introduction Mycobacterium tuberculosis remains the main cause of death as an infectious agent of Tuberculosis in humans, particularly in resource-poor settings. Worldwide, Tuberculosis is one of the top 10 causes of mortality. Objective of the study This study aims to determine the outcomes of TB treatm...

Intermittent preventive treatment of malaria in pregnancy with mefloquine in HIV-negative women: a multicentre randomized controlled trial

PloS med; 11 (9), 2014
Background: Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended by WHO to prevent malaria in African pregnant women. The spread of SP parasite resistance has raised concerns regarding long-term use for IPT. Mefloquine (MQ) is the most promising of avai...

Effect of point-of-care CD4 cell count tests on retention of patients and rates of antiretroviral therapy initiation in primary health clinics: an observational cohort study

Lancet; 378 (9802), 2011
Background: Loss to follow-up of HIV-positive patients before initiation of antiretroviral therapy can exceed 50% in low-income settings and is a challenge to the scale-up of treatment. We implemented point-of-care counting of CD4 cells in Mozambique and assessed the effect on loss to follow-up before im...