AIM

Insight into DNA Gyrase inhibition using quantitative structure-Activity relationships and structure-based drug design approaches

Derouicha, Matmour; Yassine, Merad; Houari, Toumi; Aziz, Yasri.

Batna Journal of Medical Sciences (online); 9 (2), 2022

The emergence of certain bacterial strains resistant to antibiotics has become a major public health problem, hence the need to develop new antibiotic molecules. Bacterial DNA gyrase, a type II DNA topoisomerase found in all bacteria is a proven target for antibacterial chemotherapy. Our objective is des...

Drug Design, Quantitative Structure-Activity Relationship, DNA, Bacterial, DNA Gyrase, Anti-Bacterial Agents

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Mobile phones of hospital workers: a potential reservoir for the transmission of pathogenic bacteria

Bissong, M E A; Moukou, M.

Afr. J. Clin. Exp. Microbiol; 23 (4), 2022

Background: Mobile phones are increasingly associated with the transmission of pathogenic microbial agents. In the clinical setting where there is usually high exposure to pathogens, these devices may serve as vehicles for the transmission/spread of pathogens. This study determined the prevalence of bact...

Cell Phone, DNA, Bacterial, Hospitals, Occupational Groups, Risk Factors, Cross Infection

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