AIM

In vivo efficacy of artemether-lumefantrine and artesunate-amodiaquine for the treatment of uncomplicated falciparum malaria in children: a multisite, open-label, two-cohort, clinical trial in Mozambique

Background: Mozambique adopted artemisinin-based combination therapy (ACT) for the treatment of uncomplicated Plasmodium falciparum malaria in the year 2006, and since 2009 artemether-lumefantrine (AL) and artesunateamodiaquine (ASAQ) have been proposed as alternative first-line treatments. A multicentre...

In vivo efficacy of artemether-lumefantrine and artesunate-amodiaquine for the treatment of uncomplicated falciparum malaria in children: a multisite, open-label, two-cohort, clinical trial in Mozambique

Nhama, Abel; Bassat, Quique; Enosse, Sónia; Nhacolo, Arsenio; Mutemba, Rosália; Carvalho, Eva; Naueia, Eva; Sevene, Esperança; Guinovart, Caterina; Warsame, Marian; Sanz, Sergi; Mussa, Abdul; Matsinhe, Graça; Alonso, Pedro; Tiago, Armindo; Macete, Eusebio.

Malar. j. (Online); 13 (309), 2014

Background: Mozambique adopted artemisinin-based combination therapy (ACT) for the treatment of uncomplicated Plasmodium falciparum malaria in the year 2006, and since 2009 artemether-lumefantrine (AL) and artesunate-amodiaquine (ASAQ) have been proposed as alternative first-line treatments. A multicentr...

Amodiaquine/adverse effects, Amodiaquine/therapeutic use, Antimalarials/adverse effects, Antimalarials/therapeutic use, Artemether, Lumefantrine Drug Combination, Artemisinins/adverse effects, Artemisinins/therapeutic use, Drug Combinations, Ethanolamines/adverse effects, Ethanolamines/therapeutic use, Fluorenes/adverse effects, Fluorenes/therapeutic use, Kaplan-Meier Estimate, Malaria, Falciparum/drug therapy, Malaria, Falciparum/epidemiology, Treatment Outcome, Mozambique/epidemiology

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