In vivo efficacy of artemether-lumefantrine and artesunate-amodiaquine for the treatment of uncomplicated falciparum malaria in children: a multisite, open-label, two-cohort, clinical trial in Mozambique
Malar. j. (Online); 13 (309), 2014
Background: Mozambique adopted artemisinin-based combination therapy (ACT) for the treatment of uncomplicated Plasmodium falciparum malaria in the year 2006, and since 2009 artemether-lumefantrine (AL) and artesunate-amodiaquine (ASAQ) have been proposed as alternative first-line treatments. A multicentr...
Amodiaquine/adverse effects, Amodiaquine/therapeutic use, Antimalarials/adverse effects, Antimalarials/therapeutic use, Artemether, Lumefantrine Drug Combination, Artemisinins/adverse effects, Artemisinins/therapeutic use, Drug Combinations, Ethanolamines/adverse effects, Ethanolamines/therapeutic use, Fluorenes/adverse effects, Fluorenes/therapeutic use, Kaplan-Meier Estimate, Malaria, Falciparum/drug therapy, Malaria, Falciparum/epidemiology, Treatment Outcome, Mozambique/epidemiology