AIM

Breast cancer molecular diagnostics in Rwanda: a cost-minimization study of immunohistochemistry versus a novel GeneXpert® mRNA expression assay

Erfani, Parsa; Gaga, Esther; Hakizimana, Emmanuel; Kayitare, Emmanuel; Mugunga, Jean Claude; Mugunga, Jean Claude; Shyirambere, Cyprien; Milner, Dan A; Shulman, Lawrence N; Ruhangaza, Deogratias; Fadelu, Temidayo.

Bull. W.H.O. (Online); 101 (1), 2023

Objective To compare the financial and time cost of breast cancer biomarker analysis by immunohistochemistry with that by the Xpert® STRAT4 assay. Methods We estimated costs (personnel, location, consumables and indirect) and time involved in breast cancer diagnosis at the Butaro Cancer Centre of Excell...

Breast Neoplasms, Diagnosis, Genetics, Biomarkers, Tumor, Estrogens, Immunohistochemistry, Pathology, Molecular, RNA, Messenger

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Immunohistochemical Study and Clinicopathologic Correlation of Cox-2 and Her-2 Expression in Colorectal Carcinoma: A 5-Year Retrospective Study

Odukoya, L A; Badmos, K B; Khramtsova, G; Adebayo, L A; Olopade, O I; Abdulkareem, F B.

West Afr. j. med; 39 (11), 2022

BACKGROUND: Colorectal cancer (CRC) is the fourth most common cancer in Nigeria, and it affects mostly persons in their middle age. In a bid to gain some insight into the molecular characteristics of CRC in our environment, we set out to investigate the expression of COX-2 and HER-2 among Nigerian subjec...

Colorectal Neoplasms, Cyclooxygenase 2 Inhibitors, Genes, erbB-2, Adenocarcinoma, Neoplasm, Residual, Immunohistochemistry

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Immunohistochemical Survey of Invasive Ductal Carcinoma of the Breast, using ER, PR, HER2 and KI-67 biomarkers, in Uyo, Nigeria

Eziagu, U B; Ndukwe, C O; Kudamnya, I; Peter, A I; Igiri, A O.

Ibom Medical Journal15; 15 (3), 2022

Background: Breast’s Invasive Ductal Carcinoma (IDC), which is the commonest type of malignancy in females worldwide, can be characterized using immunohistochemistry in view of personalized cancer therapy. In this study, we aimed to determine the pattern of immunohistochemical profiles of IDC using oes...

Immunohistochemistry, Flow Profiles, Triple Negative Breast Neoplasms, Carcinoma, Ductal, Carcinoma, Breast Neoplasms

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