Results: 7

Prognostic awareness and prognostic information preferences among advanced cancer patients in Kenya

Background: Cancer is the third leading cause of death in Kenya. Yet, little is known about prognostic awareness and preferences for prognostic information. Aim: To assess the prevalence of prognostic awareness and preference for prognostic information among advanced cancer patients in Kenya. Setting: Ou...

Age-group associations of schistosomiasis prevalence from trial data, Côte d’Ivoire, Kenya and the United Republic of Tanzania

Bull. W.H.O. (Print); 102 (4), 2024
Objective To determine if the prevalence of schistosomiasis in children aged 9–12 years is associated with the prevalence in 5–8-year-olds and adults after preventive chemotherapy in schools or the community. Methods We combined data from four community-randomized, preventive chemotherapy trials in t...

Assessment of substance use among injured persons seeking emergency care in Nairobi, Kenya

ntroduction: Trauma is a leading cause of morbidity and mortality in Kenya. In many countries, substance use is common among patients presenting with injuries to an emergency center (EC). Objective: To describe the epidemiology of self-reported substance use among adult injured patients seeking ED care i...

Perinatal Outcomes of Newborns by Women Presenting with Maternal Complications in Pregnancy at a County Referral Hospital in Lower Eastern Kenya

BACKGROUND Maternal complications during pregnancy and labor have been the leading cause of maternal and neonatal death globally. The aim of the study was to observe and compare the differences in the perinatal outcomes of newborns born to women with maternal complications to those born to women witho...

Predictors of Adherence to Highly Active Antiretroviral Therapy among HIV Patients attending Selected Comprehensive Care Centres in Kericho County, Kenya

Highly Active Antiretroviral Therapy (HAART) is undoubtedly the only proven remedy known to improve the health outcomes and reduce AIDS-related mortality. However, just like other chronic diseases, HIV presents significant challenges in achieving and maintaining adherence to medication. The effectivene...

VAR2CSA Serology to Detect Plasmodium falciparum Transmission Patterns in Pregnancy

Emerg. infect. dis; 25 (10), 2019
Pregnant women constitute a promising sentinel group for continuous monitoring of malaria transmission. To identify antibody signatures of recent Plasmodium falciparum exposure during pregnancy, we dissected IgG responses against VAR2CSA, the parasite antigen that mediates placental sequestration. We use...

Intermittent Preventive Treatment of Malaria in Pregnancy with Mefloquine in HIV-Infected Women Receiving Cotrimoxazole Prophylaxis: A Multicenter Randomized Placebo-Controlled Trial

PloS med; 14 (160), 2014
Background: Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended for malaria prevention in HIV-negative pregnant women, but it is contraindicated in HIV-infected women taking daily cotrimoxazole prophylaxis (CTXp) because of potential added risk of adve...