Background: Scientific information on the impact of malaria on the risk of developing type 2 diabetes mellitus (T2DM) after recovery from the coronavirus disease 2019 (COVID-19) is limited in the Ghanaian context. The purpose of this study was to examine the association between selected risk markers of...
Background: Plasmodium falciparum infection in pregnant women in sub-Saharan Africa is often asymptomatic. As these forms of malaria are often submicroscopic and difficult to diagnose by conventional methods (microscopy and/or rapid diagnostic test), diagnosis requires the use of molecular techniques suc...
Alafo, celso;
Malheia, arlindo;
Máquina, mara;
Soler, helena martí;
Aswat, ayesha S;
Koekemoer, lizette L;
Colborn, james;
Lobo, neil F;
Tatarski, allison;
Williams, yasmin A;
Marrenjo, dulcisária;
Cuamba, nelson;
Rabinovich, regina;
Alonso, Pedro;
Assessor, pedro;
Saute, francisco;
Paaijmans, krijn P.
Background: To eliminate malaria in southern Mozambique, the National Malaria Control Programme and its partners are scaling up indoor residual spraying (IRS) activities in two provinces, Gaza and Inhambane. An entomological surveillance planning tool (ESPT) was used to answer the programmatic question o...
Introduction : la présente étude avait pour objectif de ressortir certaines anomalies des enzymes hépatiques portant sur l’ASAT, l’ALAT et la LDH chez les patients impaludés en vue de contribuer à la prise en charge diagnostique du paludisme dans la ville de Butembo. Méthodes. Cette étude est ...
Introduction: Severe malaria is a leading cause of mortality due to late presentation to health facilities. Hence, there is a need to identify and mitigate factors promoting delayed presentation with severe malaria. Objective: This study aimed to evaluate determinants of delayed presentation of children ...
Nhama , Abel;
Nhamússua, Lídia;
Macete, Eusébio;
Bassat, Quique;
Salvador, Crizolgo;
Enosse, Sónia;
Candrinho, Baltazar;
Carvalho, Eva;
Nhacolo, Arsénio;
Chidimatembue, Arlindo;
Saifodine , Abuchahama;
Zulliger, Rose;
Lucchi, Naomi;
Svigel, Samaly S;
Moriarty , Leah F;
Halsey, Eric S;
Mayor, Alfredo;
Aide , Pedro.
Artemisinin-based combination therapy (ACT) has been the recommended first-line treatment for uncomplicated malaria in Mozambique since 2006, with artemether-lumefantrine (AL) and amodiaquine-artesunate (AS-AQ) as the first choice. To assess efficacy of currently used ACT, an in vivo therapeutic efficacy...
Amodiaquine,
Antimalarials/therapeutic use,
Drug Combinations,
Antimalarials/standards,
Parasitemia,
Treatment Outcome,
d0082880,
Artemether, Lumefantrine Drug Combination/pharmacology,
Artemether, Lumefantrine Drug Combination/therapeutic use,
Malaria, Falciparum/therapy,
Parasitemia/drug therapy,
Mozambique/epidemiology
Chaccour, carlos;
Zulliger, rose;
Wagman, joe;
Casellas, aina;
Nacima, amilcar;
Elobolobo, eldo;
Savaio, binete;
Saifodine, abuchahama;
Fornadel, christen;
Richardson, jason;
Robertson, molly;
Saute, francisco.
Attaining the goal of reducing the global malaria burden is threatened by recent setbacks in maintaining the effectiveness of vector control interventions partly due to the emergence of pyrethroid resistant vectors. One potential strategy to address these setbacks could be combining indoor residual spray...
Infant,
Insecticide-Treated Bednets/statistics & numerical data,
Insecticides/administration & dosage,
Organothiophosphorus Compounds/administration & dosage,
Incidence,
Mosquito Control,
Malaria, Falciparum/epidemiology,
Mozambique/epidemiology,
Organothiophosphorus Compounds/supply & distribution,
Randomized Controlled Trials as Topic
Nhama, abel;
Nhamússua, lídia;
Macete, eusébio;
Bassat, quique;
Salvador, crizolgo;
Enosse, sónia;
Candrinho, baltazar;
Carvalho, eva;
Nhacolo, arsénio;
Chidimatembue, arlindo;
Saifodine, abuchahama;
Zulliger, rose;
Lucchi, naomi;
Svigel, samaly s;
Moriarty, leah f;
Halsey, eric s;
Mayor, alfredo;
Aide, pedro.
Background: Artemisinin-based combination therapy (ACT) has been the recommended first-line treatment for uncomplicated malaria in Mozambique since 2006, with artemether–lumefantrine (AL) and amodiaquine–artesunate (AS–AQ) as the first choice. To assess efficacy of currently used ACT, an in vivo...
Mozambique/epidemiology,
Artemether/administration & dosage,
Artesunate/administration & dosage,
Algorithms,
Malaria, Falciparum,
Malaria/drug therapy,
Lumefantrine,
Infections,
Efficacy/methods,
34628,
Patients,
Parasites,
Lost to Follow-Up,
Polymerase Chain Reaction,
Recurrence,
Safety,
Therapeutics,
Molecular Diagnostic Techniques
Objectives: In 2018, malaria claimed an estimated 380,000 lives in African region, with Nigeria accounting for
24.0% (91,368) of malaria deaths from the region. Mutations in Plasmodium falciparum chloroquine resistance
transporter (Pfcrt) and P. falciparum multidrug resistance 1 (Pfmdr-1) genes had reduc...
Galatas, Beatriz;
Mayor, Alfredo;
Gupta, Himanshu;
Balanza, Núria;
Jang, Ihn Kyung;
Nhamussua, Lidia;
Simone, Wilson;
Cistero, Pau;
Chidimatembue, Arlindo;
Munguambe, Humberto;
Saute, Francisco;
Aide, Pedro;
Bassat, Quique.
An ultrasensitive malaria rapid diagnostic test (RDT) was recently developed for the improved detection of low-density Plasmodium falciparum infections. This study aimed to compare the diagnostic performance of the PfHRP2-based Abbott Malaria Ag P. falciparum ultrasensitive RDT (uRDT) to that of the conv...
Antigens, Protozoan/genetics,
Parasitology/methods,
d0077700,
d0126800,
Mozambique,
Antigens, Protozoan/blood,
Cross-Sectional Studies,
Dried Blood Spot Testing/methods,
Dried Blood Spot Testing/statistics & numerical data,
Malaria, Falciparum/diagnosis,
Parasitology/statistics & numerical data,
Plasmodium falciparum/genetics
