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Changing Trends in P. falciparum Burden, Immunity, and Disease in Pregnancy

Mayor, Alfredo; Bardají, Azucena; Macete, Eusebio; Nhampossa, Tacilta; Fonseca, Ana Maria; González, Raquel; Maculuve, Sonia; Cisteró, Pau; Rupérez, Maria; Campo, Joe; Vala, Anifa; Sigaúque, Betuel; Jiménez, Alfons; Machevo, Sonia; Fuente, Laura de la; Nhama, Abel; Luis, Leopoldina; Aponte, John J; Acácio, Sozinho; Nhacolo, Arsenio; Chitnis, Chetan; Dobaño, Carlota; Sevene, Esperanza; Alonso, Pedro Luis; Menéndez, Clara.
N. Engl. j. med; (), 2015
Background: Prevention of reinfection and resurgence is an integral component of the goal to eradicate malaria. However, the adverse effects of malaria resurgences are not known. Methods: We assessed the prevalence of Plasmodium falciparum infection among 1819 Mozambican women who delivered infants betwe...
Antibodies, Protozoan/blood, Immunoglobulin G/blood, Malaria, Falciparum/classification, Malaria, Falciparum/epidemiology, Malaria, Falciparum/immunology, Mozambique/epidemiology, Parasite Load, Parity, Plasmodium falciparum/immunology, Plasmodium falciparum/isolation & purification, Pregnancy Complications, Infectious/classification, Pregnancy Complications, Infectious/epidemiology, Pregnancy Complications, Infectious/immunology, Severity of Illness Index
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Intermittent Preventive Treatment of Malaria in Pregnancy with Mefloquine in HIV-Infected Women Receiving Cotrimoxazole Prophylaxis: A Multicenter Randomized Placebo-Controlled Trial

González, Raquel; Desai, Meghna; Macete 3, Eusebio; Ouma, Peter; Kakolwa, Mwaka A; Abdulla, Salim; Aponte, John J; Bulo, Helder; Kabanywanyi, Abdunoor M; Katana, Abraham; Maculuve, Sonia; Mayor, Alfredo; Nhacolo, Arsenio; Otieno, Kephas; Pahlavan, Golbahar; Rupérez, María; Sevene, Esperança; Slutsker, Laurence; Vala, Anifa; Williamsom, John; Menéndez, Clara.
PloS med; 14 (160), 2014
Background: Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is recommended for malaria prevention in HIV-negative pregnant women, but it is contraindicated in HIV-infected women taking daily cotrimoxazole prophylaxis (CTXp) because of potential added risk of adve...
Antimalarials/administration & dosage, Double-Blind Method, Follow-Up Studies, HIV Infections/diagnosis, HIV Infections/drug therapy, HIV Infections/epidemiology, Infectious Disease Transmission, Vertical/prevention & control, Malaria/diagnosis, Malaria/epidemiology, Malaria/prevention & control, Mefloquine/administration & dosage, Pregnancy Complications, Infectious/diagnosis, Pregnancy Complications, Infectious/epidemiology, Pregnancy Complications, Infectious/prevention & control, Pregnancy Complications, Parasitic/diagnosis, Pregnancy Complications, Parasitic/epidemiology, Pregnancy Complications, Parasitic/prevention & control, Pregnancy Outcome, Mozambique/epidemiology, Tanzania/epidemiology, Kenya/epidemiology, Trimethoprim, Sulfamethoxazole Drug Combination/administration & dosage
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