Rhinoscleroma in Malawi and Eastern Zaire

J. trop. med. hyg; 83 (5), 1980
Publication year: 1980

"The first ten cases of rhinoscleroma from Malawi and six from Eastern Zaire are reported. Most of the patients were aged between 20 and 40 years (age range 3-60) and presented with either a nasal ""tumour' or abnormalities of the nasal septum. Histological examination of biopsy material revealed features diagnostic of rhinoscleroma - a mixture of mature plasma cells and large foamy macrophages (Mikulicz cells) containing intra-cellular Gram negative bacilli. The organisms were best seen in sections stained by the Warthin-Starry technique. This study suggests that rhinoscleroma is perhaps more common in Malawi and Zaire than has been realised."

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