Inhibition of vascular endothelial growth factor (VEGF) as a novel approach for cancer therapy
Medicina (B.Aires); 60 Suppl 2 (), 2000
Of the numerous growth factors and cytokines that have been shown to have angiogenic effects, vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF), appears to be a key factor in pathological situations which involve neovascularization as well as enhanced vascular pe...
Inhibidores de la Angiogénesis/farmacología, Ensayos de Selección de Medicamentos Antitumorales, Factores de Crecimiento Endotelial/antagonistas & inhibidores, Endotelio Vascular/efectos de los fármacos, Linfocinas/antagonistas & inhibidores, Ratones Desnudos, Neoplasias Experimentales/tratamiento farmacológico, Neovascularización Patológica/tratamiento farmacológico, Ftalazinas/farmacología, Piridinas, Proteínas Tirosina Quinasas Receptoras/antagonistas & inhibidores, Receptores de Factores de Crecimiento/antagonistas & inhibidores, Receptores de Factores de Crecimiento Endotelial Vascular, Factor A de Crecimiento Endotelial Vascular, Factores de Crecimiento Endotelial Vascular