Results: 2

High Doses of Drugs Extensively Metabolized by CYP3A4 Were Needed to Reach Therapeutic Concentrations in Two Patients Taking Inducers

Chopra, Nitin; Ruan, Can-Jun; McCollum, Betsy; Ognibene, Judy; Shelton, Charles; de Leon, Jose.

Rev. colomb. psiquiatr; 49 (2), 2020

ABSTRACT Introduction: In the last 20 years of clinical practice, the senior author has identified these 2 rare cases in which the patients needed extremely high doses of drugs metabolized by CYP3A4 to reach and maintain serum therapeutic concentrations. Methods: The high metabolic ability of these 2...

Carbamazepina, Citocromo P-450 CYP3A, Diazepam, Dosificación, Inductores del Citocromo P-450 CYP3A, Palmitato de Paliperidona, Receptores Citoplasmáticos y Nucleares, Preparaciones Farmacéuticas, Triacetonamina-N-Oxil, Risperidona, Olanzapina, Fumarato de Quetiapina, Métodos

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Hyponatremia by oxcarbacepin in multiple sclerosis, a case to take account

Beltrán, Diego; Montoya, Mario.

Rev. colomb. nefrol. (En línea); 4 (2), 2017

Abstract Hyponatremia is one of the adverse effects in patients treated with oxcarbazepine. This can be seen masked by multiple symptoms which are simply attributable to other diseases, but we must always keep it in mind in a patient with a history of taking that medication. Many of patients are asymptom...

Colombia, Hiponatremia, Oxcarbazepina, Esclerosis Múltiple, Carbamazepina, Parestesia

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