Resultados: 92

Discontinuation vs continuation of renin-angiotensin system inhibition before non-cardiac surgery: a systematic review and meta-analysis

Circulation; 150 (Suppl. 1), 2024
BACKGROUND: The optimal management of angiotensin-converting enzyme (ACE) inhibitors during elective surgeries remains uncertain. While some studies suggest that continuing ACE inhibitors increase the risk of perioperative hypotension, others argue that discontinuation may heighten the risk of significan...

Atorvastatin therapy for prevention of anthracycline-induced cardiotoxicity in cancer patients: a meta-analysis

Circulation; 150 (Suppl. 1), 2024
INTRODUCTION: Cancer therapy-induced cardiac dysfunction is a significant adverse effect of chemotherapeutic agents, particularly anthracyclines (ANT). High-potency statin therapy, such as atorvastatin, appears to exert a protective effect against this condition. OBJECTIVE: We aimed to perform a meta-ana...

SGLT2 Inhibitors following acute myocardial infarction: a systematic review and meta-analysis

Circulation; 150 (Suppl. 1), 2024
BACKGROUND: Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have demonstrated cardiovascular benefits in various settings. However, their impact after myocardial infarction (MI) in patients without prior heart failure remains unclear. Therefore, we conducted a meta-analysis comparing SGLT2i to placebo...

Diagnostic accuracy of artificial intelligence-based electrocardiogram algorithm to predict heart failure with reduced ejection fraction: a systematic review and meta-analysis

Circulation; 150 (Suppl. 1), 2024
INTRODUCTION: AI-based EKG has shown good accuracy for diagnosing heart failure. However, due to the heterogeneity of studies regarding cutoff points, its precision for specifically detecting heart failure with reduced ejection fraction (LVEF <40%) is not yet well established. Research question: What it ...

Identifying the impact of systolic dysfunction on CKD risk in HFpEF patients

Circulation; 150 (Suppl. 1), 2024
INTRODUCTION: Chronic kidney disease (CKD) is a critical comorbidity in heart failure with preserved ejection fraction (HFpEF), often linked to congestion due to elevated filling pressures. However, the role of subtle systolic dysfunction in CKD remains to be elucidated. This study aimed to investigate t...

Uso de beta-bloqueadores com dobutamina em pacientes com insuficiência cardíaca avançada em fila de transplante cardíaco: um estudo observacional
Use of beta-blockers with dobutamine in patients with advanced heart failure on a heart transplant waiting list: an observational study

Int. j. cardiovasc. sci. (Impr.); 37 (suppl. 12), 2024
FUNDAMENTO: Devido à grande quantidade de receptores para transplante de coração (TxC) e a falta de doadores, a fila de espera mesmo em prioridade por dependência inotrópica pode ser longa. Os beta-bloqueadores (BB) são fármacos de primeira linha no tratamento da insuficiência cardíaca de fraç...

Retransplante cardíaco sequencial: uma história de sucesso após 3 enxertos em paciente com Doença de Chagas
Sequential heart retransplantation: a success story after 3 grafts in a patient with Chagas disease

Int. j. cardiovasc. sci. (Impr.); 37 (suppl. 12), 2024
FUNDAMENTO: A sobrevida dos pacientes transplantados aumentou nas últimas décadas, assim como suas complicações agudas e tardias, tornando o retransplante cardíaco (RTxC) uma opção do tratamento, compondo 3% dos transplantes realizados no mundo. RELATO DE CASO: Paciente do sexo feminino, 59 anos, ...

Uso prolongado da bomba de balão intra-aórtico: uma estratégia segura?
Prolonged use of intra-aortic balloon pump: a safe strategy?

Int. j. cardiovasc. sci. (Impr.); 37 (suppl. 12), 2024
FUNDAMENTO: O transplante cardíaco (TC) é a terapia principal na insuficiência cardíaca avançada (ICA) refratária ao tratamento clínico otimizado. O balão intra-aórtico (BIA) é um dispositivo de assistência ventricular que auxilia na estabilidade hemodinâmica quando há deterioração clínic...

Amiodarone or implantable cardioverter-defibrillator in chagas cardiomyopathy: the CHAGASICS randomized clinical trial

IMPORTANCE: Over 10 000 people with Chagas disease experience sudden cardiac death (SCD) annually, mostly caused by ventricular fibrillation. Amiodarone hydrochloride and the implantable cardioverter-defibrillator (ICD) have been empirically used to prevent SCD in patients with chronic Chagas cardiomyopa...

Fatores de risco, manejo e evolução após primeiro infarto agudo do miocárdio: Um estudo de mundo real comparando coortes de mulheres e homens na rede TriNetX
Risk Factors, Management, and Evolution after the First Acute Myocardial Infarction: A Real-World Study Comparing Cohorts of Women and Men in the TriNetX Network

Arq. bras. cardiol; 121 (10), 2024
FUNDAMENTO: Estudos de coorte internacionais têm consistentemente demonstrado ao longo das últimas décadas um prognóstico desfavorável em pacientes do sexo feminino após o primeiro infarto agudo do miocárdio. No entanto, dados nacionais sobre esse tema são limitados. OBJETIVOS: O presente estudo ...