Despite intense efforts, the number of new cases of leprosy has remained significantly high over the past 20 years. Host genetic background is strongly linked to the pathogenesis of this disease, which is caused by Mycobacterium leprae (M. leprae), and there is a consensus that the most significant genet...
Background: Innovative approaches are required for leprosy control to reduce cases and curb transmission of Mycobacterium leprae. Early case detection, contact screening, and chemoprophylaxis are the most promising tools. We aimed to generate evidence on the feasibility of integrating contact tracing and...
Objetivo: Analisar as produções científicas sobre a efetividade dos inibidores da enzima Janus-Kinase (iJAK) no tratamento da Alopecia Areata. Métodos: Realizou-se uma revisão integrativa de artigos publicados no período de 2015 a 2020, nos idiomas inglês, português e espanhol que contemplassem a...