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Sacubitril-Valsartan lowers atrial fibrillation recurrence and left atrial volume post-catheter ablation: systematic review and meta-analysis

de Lucena, Larissa Araújo; Freitas, Marcos Aurélio Araújo; Guida, Camila Mota; Hespanhol, Larissa C; de Sousa, Ana Karenina C; de Sousa, Júlio César V; Maia, Ferdinand Gilbert S.

Am. j. cardiovasc. drugs; 25 (2), 2025

INTRODUCTION: In patients with atrial fibrillation (AF) who have undergone catheter ablation, the comparative effectiveness of sacubitril-valsartan (SV) versus ACE inhibitors (ACEi) or angiotensin-receptor blockers (ARB) in preventing AF recurrence remains unclear. The purpose of the present systematic r...

Fibrilação Atrial/tratamento farmacológico, Valsartana/uso terapêutico, Compostos de Bifenilo/uso terapêutico, Ablação por Cateter/métodos, Combinação de Medicamentos, Aminobutiratos/uso terapêutico, Antagonistas de Receptores de Angiotensina/uso terapêutico, Recidiva, Átrios do Coração, Ensaios Clínicos Controlados Aleatórios como Assunto, Tetrazóis/administração & dosagem, Volume Sistólico/efeitos dos fármacos

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Combined left atrial appendage occlusion and catheter ablation for atrial fibrillation versus isolated left atrial appendage occlusion: A systematic review and meta-analysis

BACKGROUND: Data on the effects of combined left atrial appendage occlusion (LAAO) and catheter ablation (CA) for atrial fibrillation (AF) remain limited. We aimed to perform a systematic review and meta-analysis comparing LAAO and CA versus isolated LAAO. METHODS: We systematically searched PubMed, Emba...