Pivatto Júnior, Fernando;
Santos, Ângela Barreto Santiago;
Englert, Eduarda Foresti;
Mazzutti, Géris;
Costa, Guilherme Oliveira Magalhães;
Saffi, Marco Aurélio Lumertz;
Siebert, Marina;
Liedke, Pedro Emanuel Rubini;
Fritsch, Vinícius Henrique;
Biolo, Andreia.
BACKGROUND: The classic biomarkers troponin and brain natriuretic peptide (BNP), as well as the currently available risk scores, are far from being considered ideal for predicting cancer therapy-related cardiac dysfunction (CTRCD). MicroRNAs (miRNAs) are promising biomarkers for better identification of ...
BACKGROUND: Chagas cardiomyopathy (ChCM) is a severe form of Chagas disease and a major cause of cardiovascular morbidity and mortality. The dysregulation of the immune response leads to cardiac remodeling and functional disruptions, resulting in life-threatening complications. Conventional diagnostic me...
Tavares, Isabela Rodrigues;
Caffaro, Roberto Augusto;
Portugal, Maria Fernanda;
Ribeiro, Camilla Moreira;
da Silva, Viviane Santana;
Krupa, Emily;
Nikolovski, Srdjan;
de Britto, Karen Falcão;
Gomes Pereira Petisco, Ana Cláudia;
Miranda, Maria Cristina;
Santos, Sandra Gomes de Souza;
Dourado, Marcela da Silva;
Siqueira, Paula Veloso;
Siddiqui, Fakiha;
Fareed, Jawed;
Ramacciotti, Eduardo.
Venous thromboembolism (VTE), including deep venous thrombosis (DVT) and pulmonary embolism (PE), represents a substantial healthcare challenge. Provoked and unprovoked DVT cases carry distinct risks and treatment considerations. Recognizing the limitations of this classification, molecular markers may e...
Cerda, Alvaro;
Bortolin, Raul Hernandes;
Yoshinaga, Marcos Yukio;
Freitas, Renata Caroline Costa de;
Dagli-Hernandez, Carolina;
Borges, Jessica Bassani;
Oliveira, Victor Fernandes de;
Gonçalves, Rodrigo Marques;
Faludi, Andre Arpad;
Bastos, Gisele Medeiros;
Hirata, Rosario Dominguez Crespo;
Hirata, Mario Hiroyuki.
Familial hypercholesterolemia (FH) is a disorder of lipid metabolism that causes elevated low-density lipoprotein cholesterol (LDL-c) and increased premature atherosclerosis risk. Statins inhibit endogenous cholesterol biosynthesis, which reduces LDL-c plasma levels and prevent from cardiovascular events...
Santos, Karina Gama Dos;
Yoshinaga, Marcos Yukio;
Glezer, Isaias;
Chaves-Filho, Adriano de Britto;
Santana, Aline Alves de;
Kovacs, Cristiane;
Magnoni, Carlos Daniel;
Lajolo, Franco Maria;
Miyamoto, Sayuri;
Hassimotto, Neuza Mariko Aymoto.
BACKGROUND & AIMS: Dyslipidaemia is usually common in obesity, insulin resistance, and type 2 diabetes mellitus. Clinical trials suggest that orange juice may have a positive impact on lipid metabolism and blood lipid profiles; however conflicting results have been reported. Here, we applied a combined u...
Brochet, Pauline;
Ianni, Barbara;
Nunes, João P S;
Frade, Amanda F;
Teixeira, Priscila C;
Mady, Charles;
Ferreira, Ludmila R P;
Kuramoto, Andreia;
Pissetti, Cristina W;
Saba, Bruno;
Cândido, Darlan D S;
Dias, Fabrício;
Sampaio, Marcelo;
Marin-Neto, José A;
Fragata, Abílio;
Zaniratto, Ricardo C F;
Siqueira, Sergio;
Peixoto, Giselle D L;
Rigaud, Vagner O C;
Buck, Paula;
Almeida, Rafael R;
Lin-Wang, Hui Tzu;
Schmidt, André;
Martinelli, Martino;
Hirata, Mario H;
Donadi, Eduardo;
Rodrigues Jr, Virmondes;
Pereira, Alexandre C;
Kalil, Jorge;
Spinelli, Lionel;
Cunha-Neto, Edecio;
Chevillard, Christophe.
Chagas disease is a parasitic disease from South America, affecting around 7 million people worldwide. Decades after the infection, 30% of people develop chronic forms, including Chronic Chagas Cardiomyopathy (CCC), for which no treatment exists. Two stages characterized this form: the moderate form, cha...
Silva, Renata Alves da;
Bersch-Ferreira, Angela Cristina;
Gehringer, Marcella Omena;
Ross-Fernandes, Maria Beatriz;
Amaral, Cristiane Kovacs do;
Wang, Hui-Tzu Lin;
Lima, Paula Helena;
Lima, Patrícia Azevedo de;
França, João Italo;
Weber, Bernardete;
Magnoni, Carlos Daniel;
Rogero, Marcelo Macedo.
Summary Background & aims: Diet is a modifiable risk factor, which may influence the gene expression and the concentration of inflammatory biomarkers related to obesity and atherosclerosis. In this sub study from Brazilian Cardioprotective Nutritional (BALANCE) Program, we hypothesized that a nutritional...
Background: Erythema nodosum leprosum (ENL) is a frequent complication of multibacillary leprosy
that can result in significant morbidity, including peripheral nerve damage and physical disability. The
identification of possible serum markers could be a valuable tool for the early detection of ENL. Aim...
Isquemia Miocárdica/diagnóstico por imagem,
Isquemia Miocárdica/congênito,
Ventrículos do Coração/patologia,
Dor no Peito/complicações,
Hipertensão/complicações,
Fibrose Endomiocárdica/complicações,
Ecocardiografia sob Estresse/métodos,
Biomarcadores,
Angiografia Coronária/métodos,
Cateterismo Cardíaco/métodos,
Dobutamina/efeitos adversos
