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Renal medulla in hypertension

Cowley Jr, Allen W; Roman, Richard J; Mattson, David L; Franchini, Kleber G; O’Connor, Paul M; Makino, Ayako; Taylor, Norman E; Evans, Louise C; Mori, Takefumi; Dickhout, Jeffrey G; Jin, Chunhua; Miyata, Noriyuki; Nakanishi, Kazushige; Szentiványi Jr, Mátyás; Park, Frank; Skelton, Meredith M; Kurth, Theresa; Shimada, Satoshi.
Hypertension; 81 (), 2024
Abstract: Studies have found that blood flow to the renal medulla is an important determinant of pressure-natriuresis and the long-term regulation of arterial pressure. First, a brief review of methods developed enabling the study of the medullary circulation is presented. Second, studies performed in ra...
Fluxometria por Laser-Doppler, Óxido Nítrico, Espécies Reativas de Oxigênio, Natriurese, Hipertensão, Vasoconstritores
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GPCRs overexpression and impaired fMLP-induced functions in neutrophils from chronic kidney disease patients

Scharf, Pablo; Sandri, Silvana; Rizzetto, Felipe; Xavier, Luana Filippi; Grosso, Daniela; Correia-Silva, Rebeca D; Farsky, Pedro S; Gil, Cristiane D; Farsky, Sandra Helena Poliselli.
Front. immunol; 15 (), 2024
INTRODUCTION: G-protein coupled receptors (GPCRs) expressed on neutrophils regulate their mobilization from the bone marrow into the blood, their half-live in the circulation, and their pro- and anti-inflammatory activities during inflammation. Chronic kidney disease (CKD) is associated with systemic inf...
Neutrófilos/metabolismo, Receptores de Formil Peptídeo/metabolismo, Insuficiência Renal Crônica/metabolismo, Receptores Acoplados a Proteínas G/metabolismo, Espécies Reativas de Oxigênio/metabolismo, Receptores de Lipoxinas/metabolismo, Receptores CXCR4/metabolismo, Nefropatias
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