Resultados: 3

Unveiling the impact of hypodermis on gene expression for advancing bioprinted full-thickness 3D skin models

Commun Biol; 7 (1), 2024
3D skin models have been explored as an alternative method to the use of animals in research and development. Usually, human skin equivalents comprise only epidermis or epidermis/dermis layers. Herein, we leverage 3D bioprinting technology to fabricate a full-thickness human skin equivalent with hypoderm...

microRNAs e seus mecanismos de regulação gênica na toxoplasmose gestacional

A toxoplasmose é uma zoonose cosmopolita e quando a infecção ocorre durante a gravidez (toxoplasmose gestacional) o parasita pode atravessar a placenta, causando a forma congênita, e causar danos graves. Investigar como os microRNAs regulam a infecção pode oferecer informações valiosas sobre sua ...

Effect of qualitative and quantitative nutritional plan on gene expression in obese patients in secondary prevention for cardiovascular disease

Clin Nutr ESPEN; (41), 2021
Summary Background & aims: Diet is a modifiable risk factor, which may influence the gene expression and the concentration of inflammatory biomarkers related to obesity and atherosclerosis. In this sub study from Brazilian Cardioprotective Nutritional (BALANCE) Program, we hypothesized that a nutritional...