The respiratory tract is considered the main port of entry of Mycobacterium leprae, the
causative agent of leprosy. However, the great majority of individuals exposed to the
leprosy bacillus will never manifest the disease due to their capacity to develop protective
immunity. Besides acting as a physical...
Schwann cells (SCs) critically maintain the plasticity of the peripheral nervous system. Peripheral nerve injuries and infections stimulate SCs in order to retrieve homeostasis in neural tissues. Previous studies indicate that Mycobacterium leprae (ML) regulates the expression of key factors related to S...