Resultados: 91

Renal medulla in hypertension

Hypertension; 81 (), 2024
Abstract: Studies have found that blood flow to the renal medulla is an important determinant of pressure-natriuresis and the long-term regulation of arterial pressure. First, a brief review of methods developed enabling the study of the medullary circulation is presented. Second, studies performed in ra...

Blood pressure control and clinical outcomes after renal denervation through irrigated catheter radiofrequency ablation in patients with resistant hypertension: A case series with up to 10 years of follow-up

INTRODUCTION: The long-term efficacy of renal denervation (RDN) has not been extensively documented. AIM: To describe the long-term follow-up of patients after RDN. METHODS: We evaluated patients with resistant hypertension (RH) who underwent RDN with irrigated catheter from 2012 to 2014 at a single cent...

Discontinuation vs continuation of renin-angiotensin system inhibition before non-cardiac surgery: a systematic review and meta-analysis

Circulation; 150 (Suppl. 1), 2024
BACKGROUND: The optimal management of angiotensin-converting enzyme (ACE) inhibitors during elective surgeries remains uncertain. While some studies suggest that continuing ACE inhibitors increase the risk of perioperative hypotension, others argue that discontinuation may heighten the risk of significan...

DOACs versus aspirin for secondary prevention of stroke after ESUS: an updated systematic review and meta-analysis of randomized clinical trials

Circulation; 150 (Suppl. 1), 2024
BACKGROUND: Embolic stroke of undetermined source (ESUS) is a nonlacunar ischemic stroke with no clear cause, having a 4%-5% annual recurrence rate. The potential benefits of direct oral anticoagulants (DOACs) relative to aspirin in patients with ESUS remain unclear. OBJECTIVE: We aimed to perform a syst...

Key performance indicators of secondary health care in chronic kidney disease: experience in public and private Services in the state of São Paulo, Brazil

Int J Nephrol; (), 2024
INTRODUCTION: The objective of this study was to evaluate quality indicators of secondary health care in chronic kidney disease (CKD). METHODS: This retrospective longitudinal study was conducted in an outpatient medical nephrology clinic of the Brazilian Unified Health System (UHS) and a multidisciplina...

Systematic review and meta-analysis of second-generation sham-controlled randomized trials of renal denervation therapy for patients with hypertension

INTRODUCTION: Renal denervation has been associated with substantial and sustained blood pressure reduction and is considered to serve as an alternative treatment for patients with resistant hypertension. However, the first published SHAM-controlled trial assessing RDN safety and efficacy showed no diffe...

Bevacizumab-induced hypertension in patients with glioblastoma: a systematic review and meta-analysis

Eur. heart j; 45 (Suppl. 1), 2024
BACKGROUND: Bevacizumab is a monoclonal antibody medication used as standard treatment for different types of cancers, one of them is glioblastoma, which is the most common primary brain tumor. PURPOSE: We aimed to assess bevacizumab and its effects on inducing hypertension in patients with glioblastoma....

Comparison of intensive treatment versus standard treatment in lowering blood pressure and its association with cognitive decline and dementia: a systematic review and meta-analysis

Eur. heart j; 45 (Suppl. 1), 2024
BACKGROUND: The ideal blood pressure target level for preventing cognitive decline or dementia in patients with systemic arterial hypertension (SAH) remains unclear. PURPOSE: This study aims to investigate whether intensive blood pressure reduction compared to standard treatment is associated with a redu...

Assessing the efficacy of renal denervation in patients with resistant arterial hypertension: a systematic review and meta-analysis

Eur. heart j; 45 (Suppl. 1), 2024
BACKGROUND/INTRODUCTION: Renal denervation (RDN) is an innovative procedure designed to regulate the renal sympathetic nervous system for the control of arterial hypertension (HTN). RDN emerges as an alternative for patients with resistant arterial hypertension. Despite this, the clinical efficacy of RDN...