Lipidomic analysis identified potential predictive biomarkers of statin response in subjects with Familial hypercholesterolemia
Chem. Phys. lipids; 257 (), 2023
Familial hypercholesterolemia (FH) is a disorder of lipid metabolism that causes elevated low-density lipoprotein cholesterol (LDL-c) and increased premature atherosclerosis risk. Statins inhibit endogenous cholesterol biosynthesis, which reduces LDL-c plasma levels and prevent from cardiovascular events...