Immunotherapy treatments that target programmed cell death receptor-1 (PD-1) or its ligand (PD-L1) have revolutionized the treatment of metastatic melanoma and currently represent the standard first-line treatment for this type of cancer. However, it is still not entirely clear which biomarkers are cost-...
BACKGROUND: It is suggested that survivors of different types of cancer may have an increased risk of stroke. Our study aims to evaluate cancer patients and non-cancer controls by analyzing stroke events in each group. Previous studies concluded that certain types of cancer increased stroke risk, however...
BACKGROUND: Fluoropyrimidines are chemotherapy drugs utilized to treat a variety of solid tumors. These drugs predominantly rely on the enzyme dihydropyrimidine dehydrogenase (DPD), which is encoded by the DPYD gene, for their metabolism. Genetic mutations affecting this gene can cause DPYD deficiency, d...
Oliveira, Gustavo;
Pasqualotto, Eric;
Balieiro, Caroline;
Nienkötter, Thiago;
Silva, Ana Laura Soares;
Carvalho, Henrique Champs Porfírio;
Minucci, Barbara Silvestre;
Cintra, Júlia;
Kabariti, Júlia;
Zapparoli, Isabella;
Borges, Maria Eduarda Stacciarini;
Moreira, Maria Eduarda Liporaci;
Assunção, Marcela;
Maluf, Pâmela;
Guida, Camila Mota.
BACKGROUND: The impact of cancer on patients with atrial fibrillation (AF) on warfarin remains a topic of ongoing debate. METHODS: We performed a systematic review and meta-analysis exploring the effect of cancer in patients with AF on warfarin. We searched PubMed, Embase, and Cochrane for eligible trial...
Oliveira, Gustavo;
Balieiro, Caroline;
Pasqualotto, Eric;
Zapparoli, Júlia;
Kabariti, Isabella;
Cintra, Júlia;
Silva, Ana Laura Soares;
Minucci, Barbara;
Frange, Leonardo Cunha;
Maluf, Marcela;
Moreira, Maria Eduarda Liporaci;
Carvalho, Henrique Champs Porfírio;
Assunção, Pâmela;
Guida, Camila Mota.
BACKGROUND: The impact of cancer on patients with atrial fibrillation (AF) on direct oral anticoagulants (DOACs) remains a matter of debate. METHODS: We conducted a systematic review and meta-analysis exploring the effect of personal history of cancer in patients with AF on DOACs. PubMed, Embase, and Coc...
BACKGROUND: Cancer survivors are at increased risk for atrial fibrillation (AF). However, data on the efficacy and safety of catheter ablation (CA) in this population remain limited. Therefore, we aimed to perform a systematic review and meta-analysis comparing outcomes after CA for AF in patients with v...
RESUMO Contexto: A desobstrução da árvore biliar e a drenagem da bile são elementos esperados na fisiologia humana e podem ser realizadas por meio de técnicas paliativas amplamente utilizadas, como a drenagem biliar trans-hepática percutânea, Percutaneous Transhepatic Biliary Drainage (PTBD) e dre...
Contexto: o acesso igualitário aos serviços de saúde no Brasil é universal, gratuito e sem discriminação. No âmbito da saúde da mulher, foram estabelecidos programas no Sistema Único de Saúde (SUS) para beneficiar as mulheres.
Objetivo: apontar alternativas disponíveis para o aprimoramento ao...
BACKGROUND: Patients with an active or past medical history of cancer have an increased risk of atrial fibrillation (AF) and drug-refractory AF. However, evidence for the safety and efficacy of catheter ablation in this population remains limited. HYPOTHESIS: Catheter ablation is a safe and effective str...
Análise de perfil epidemiológico e a tendência da mortalidade de professores da educação básica e do ensino superior no Estado de Goiás, no período de 2008 a 2017. Método: série temporal, com dados do Sistema de Informações sobre Mortalidade. Para a análise da tendência da mortalidade utili...
