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Performance of the tetra-primer PCR technique compared to PCR-RFLP in the search for rs12979860 (C/T) and rs8099917 (T/G) single nucleotide polymorphisms (SNPs) in the IFNL4 gene

Kindermann, Ellen Hochleitner Souza; Campos, Karoline Rodrigues; Caterino-de-Araujo, Adele.
Rev. Inst. Adolfo Lutz (Online); 82 (), 2023
Single nucleotide polymorphisms (SNPs, rs12979860 e rs8099917) in the Interferon Lambda 4 gene (IFNL4, formerly IFNL3and/or IL28B) has been associated with failure in the innate immune response, sustained virological response in hepatitis C, and HTLV-1-associated myelopathy (HAM) development. To search...
Interferon lambda, Interleucinas, Polimorfismo de Nucleotídeo Único, Reação em Cadeia da Polimerase, Polimorfismo de Fragmento de Restrição
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ACAT-1 gene rs1044925 SNP and its relation with different clinical forms of chronic Chagas disease

Carvalho, Thaysa Buss; Padovani, Carlos Roberto; Oliveira Junior, Luiz Roberto de; Latini, Ana Carla Pereira; Kurokawa, Cilmery Suemi; Pereira, Paulo Câmara Marques; Santos, Rodrigo Mattos dos.
Chagas disease, caused by the protozoan Trypanosoma cruzi (T. cruzi), although discovered more than a century ago, is still a not very well-elucidated aspect. Individuals in the chronic phase of the disease may present asymptomatic clinical form or symptomatologies related to the cardiac, digestive syste...
Doença de Chagas/genética, Polimorfismo de Nucleotídeo Único, Esterol O-Aciltransferase/genética, Doenças Assintomáticas, Doença de Chagas/parasitologia, Trypanosoma cruzi/fisiologia, Polimorfismo de Fragmento de Restrição