Resultados: 5

DOACs versus aspirin for secondary prevention of stroke after ESUS: an updated systematic review and meta-analysis of randomized clinical trials

Circulation; 150 (Suppl. 1), 2024
BACKGROUND: Embolic stroke of undetermined source (ESUS) is a nonlacunar ischemic stroke with no clear cause, having a 4%-5% annual recurrence rate. The potential benefits of direct oral anticoagulants (DOACs) relative to aspirin in patients with ESUS remain unclear. OBJECTIVE: We aimed to perform a syst...

Could a lipid oxidative biomarker be applied to improve risk stratification in the prevention of cardiovascular disease?

Biomed. pharmacother; 160 (114345), 2023
There is significant evidence demonstrating the influence of oxidative stress on atherosclerosis and cardiovascular diseases (CVD). However, oxidative biomarkers have not been applied to follow patients under primary or secondary prevention. Many factors can explain this paradox: the higher complexity of...

Intrinsecoid deflection as a risk predictor for sudden cardiac death in hypertrophic cardiomyopathy

Arq. bras. cardiol; 119 (5 supl.1), 2022
INTRODUCTION: Sudden Cardiac Death (SCD) and Malignant Ventricular Arrhythmias (MVA) in patients with Hypertrophic Cardiomyopathy (HCM) occurs in up to 0.9%/ year. Identifying risk predictors for such an event is of paramount importance, considering the indication of Implantable Cardiodefibrillator (ICD)...

The effect of the a regional cardioprotective nutritional program on inflammatory biomarkers and metabolic risk factors in secondary prevention for cardiovascular disease, a randomised trial

Clin. nutr. (Edinb.); 40 (6), 2021
BACKGROUND & AIMS: To evaluate the effect of the Brazilian Cardioprotective Diet Program (BALANCE Program) on inflammatory biomarkers, involved in the pathophysiology of the atherosclerosis, on inflammatory biomarkers, cardiovascular risk factors, and on plasma fatty acids in cardiovascular disease secon...

Challenges and Opportunities to Scale Up Cardiovascular Disease Secondary Prevention in Latin America and the Caribbean

Glob. heart (Online); 13 (2), 2018
Cardiovascular disease (CVD) is the leading cause of death throughout the world; however, a reduction of 21% (age-standardized cardiovascular mortality rates per 100,000 inhabitants) was observed between 1990 and 2010, with more substantial reductions in CVD mortality evident in high-income countries (w4...