Resultados: 2

PD-1/PD-l1 inhibitors increase pathological complete response in locally advanced gastric cancer: a meta-analysis and trial sequential analysis

de Moraes, Francisco Cezar Aquino; Sano, Vitor Kendi Tsuchiya; Silva, Barbara Lins; Silva, Ana Laura Soares; Castro, Stellanny Cilene Rodrigues; Kreuz, Michele; Fernandes, Lilianne Rodrigues; Kelly, Francinny Alves; Burbano, Rommel Mario Rodríguez.

J. gastrointest. cancer (Online); 56 (1), 2025

BACKGROUND AND OBJECTIVE: Gastric cancer (GC) remains a leading cause of morbidity and mortality worldwide. The current standard of care involves neoadjuvant chemotherapy (NACT) followed by radical gastrectomy. This study aims to evaluate the efficacy of neoadjuvant therapy with PD-1/PD-L1 inhibitors in ...

Neoplasias Gástricas/tratamento farmacológico, Inibidores de Checkpoint Imunológico/uso terapêutico, Terapia Neoadjuvante/métodos, Antígeno B7-H1, Receptor de Morte Celular Programada 1, Gastrectomia

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The use of steroids associated with PD1/PDL-1 blockage in patients with brain metastasis: a systematic review and meta-analysis

Moraes, F. C. A. D; Silva, B. L; Sano, V. K. T; Fernandes, L. Rodrigues; Kreuz, M; Kelly, F.

Ann. oncol; 35 (Suppl. 2), 2024

BACKGROUND: Brain metastases (BMs) represent the most common intracranial neoplasms in adults, affecting up to 25% of patients with metastatic cancers. Primary cancers of the lung, melanoma and colorectal are responsible for the majority of diagnosed BMs. Current therapies for BMs include stereotactic ra...

Neoplasias Encefálicas, Esteroides, Receptor de Morte Celular Programada 1

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