INTRODUCTION: AI-based EKG has shown good accuracy for diagnosing heart failure. However, due to the heterogeneity of studies regarding cutoff points, its precision for specifically detecting heart failure with reduced ejection fraction (LVEF <40%) is not yet well established. Research question: What it ...
OBJECTIVE: To evaluate the diagnostic sensitivity and specificity of ST-segment elevation on a 12‑lead ECG in detecting ACO across any coronary artery, challenging the current STEMI-NSTEMI paradigm.
METHODS: Studies from MEDLINE and Scopus (2012-2023) comparing ECG findings with coronary angiograms wer...
We assessed the performance of MTBDRsl for detection of resistance to fluoroquinolones, aminoglycosides/cyclic peptides, and ethambutol compared to BACTEC MGIT 960 by subjecting simultaneously to both tests 385 phenotypically multidrug-resistant-Mycobacterium tuberculosis isolates from Sao Paulo, Brazil....
Although multidrug therapy is considered an effective treatment for leprosy, antimicrobial resistance is a
serious concern. We performed a systematic review of studies on the diagnostic accuracy and screening of
tests for antimicrobial resistance in leprosy. This review was registered in PROSPERO (CRD420...
Introduction: Brazil ranks first in the number of HTLV-1/-2-infected individuals worldwide. The high morbidity and mortality of HTLV-1-associated diseases, especially following infection in infancy, requires strong action to reduce vertical transmission. Methods: To facilitate the appraisal of the implem...
Leprosy is difficult to diagnose since it is caused by a bacterium that does not grow in vitro. Bacilli direct detection or the presence of specific antibodies can vary greatly depending on the clinical form. M. leprae direct DNA detection can aid clinical diagnosis, although invasive skin biopsies are s...
A saúde pública tem como grande desafio a detecção precoce de casos novos de tuberculose (TB), principalmente aqueles apresentando resistência aos fármacos anti-TB. Pacientes bacilíferos podem transmitir cepas de M. tuberculosis (Mt) resistentes nas comunidades quando não prontamente identificado...
O rastreamento do câncer do colo uterino é realizado por meio da citologia cervical e colposcopia. O objetivo deste estudo foi avaliar a acurácia da citologia cervical e da colposcopia para o diagnóstico de neoplasia intraepitelial cervical no do Centro Estadual de Oncologia. Para tanto, utilizou-se ...