Resultados: 8

Diagnostic accuracy of artificial intelligence-based electrocardiogram algorithm to predict heart failure with reduced ejection fraction: a systematic review and meta-analysis

Circulation; 150 (Suppl. 1), 2024
INTRODUCTION: AI-based EKG has shown good accuracy for diagnosing heart failure. However, due to the heterogeneity of studies regarding cutoff points, its precision for specifically detecting heart failure with reduced ejection fraction (LVEF <40%) is not yet well established. Research question: What it ...

Systematic review and meta-analysis of diagnostic test accuracy of ST-segment elevation for acute coronary occlusion

Int. j. cardiol; 402 (), 2024
OBJECTIVE: To evaluate the diagnostic sensitivity and specificity of ST-segment elevation on a 12‑lead ECG in detecting ACO across any coronary artery, challenging the current STEMI-NSTEMI paradigm. METHODS: Studies from MEDLINE and Scopus (2012-2023) comparing ECG findings with coronary angiograms wer...

GenoType MTBDRsl for detection of second-line drugs and ethambutol resistance in multidrug-resistant Mycobacterium tuberculosis isolates at a high-throughput laboratory

We assessed the performance of MTBDRsl for detection of resistance to fluoroquinolones, aminoglycosides/cyclic peptides, and ethambutol compared to BACTEC MGIT 960 by subjecting simultaneously to both tests 385 phenotypically multidrug-resistant-Mycobacterium tuberculosis isolates from Sao Paulo, Brazil....

A systematic review and meta-analysis of studies on the diagnostic accuracy and screening of tests to detect antimicrobial resistance in leprosy

Although multidrug therapy is considered an effective treatment for leprosy, antimicrobial resistance is a serious concern. We performed a systematic review of studies on the diagnostic accuracy and screening of tests for antimicrobial resistance in leprosy. This review was registered in PROSPERO (CRD420...

Specificity of HTLV screening tests and its impact on health care program costs: The perspective of antenatal screening in Brazil

Rev Soc Bras Med Trop; 54 (), 2021
Introduction: Brazil ranks first in the number of HTLV-1/-2-infected individuals worldwide. The high morbidity and mortality of HTLV-1-associated diseases, especially following infection in infancy, requires strong action to reduce vertical transmission. Methods: To facilitate the appraisal of the implem...

Ultra-sensitive detection of Mycobacterium leprae: DNA extraction and PCR assays

Leprosy is difficult to diagnose since it is caused by a bacterium that does not grow in vitro. Bacilli direct detection or the presence of specific antibodies can vary greatly depending on the clinical form. M. leprae direct DNA detection can aid clinical diagnosis, although invasive skin biopsies are s...

Proposta de mudança no protocolo de realização do teste de sensibilidade para tuberculose no Laboratório Central de Saúde Pública Prof. Gonçalo Moniz: rapidez e descoberta oportuna dos casos de TB com resistência ampliada na Bahia

A saúde pública tem como grande desafio a detecção precoce de casos novos de tuberculose (TB), principalmente aqueles apresentando resistência aos fármacos anti-TB. Pacientes bacilíferos podem transmitir cepas de M. tuberculosis (Mt) resistentes nas comunidades quando não prontamente identificado...

Acurácia da citologia vaginal e colposcopia para diagnóstico de neoplasia intraepitelial cervical no CICAN-Bahia

O rastreamento do câncer do colo uterino é realizado por meio da citologia cervical e colposcopia. O objetivo deste estudo foi avaliar a acurácia da citologia cervical e da colposcopia para o diagnóstico de neoplasia intraepitelial cervical no do Centro Estadual de Oncologia. Para tanto, utilizou-se ...