SUMMARY OBJECTIVE To investigate the relations of T lymphocytes, cytokines, immunoglobulin E, and nitric oxide with otitis media with effusion (OME) in children and their clinical significances. METHODS Fifty children with OME treated in our hospital were enrolled in the study (observation group). Fi...
Linfocitos T CD4-Positivos,
Linfocitos T CD8-positivos,
Estudios de Casos y Controles,
Citocinas/sangre,
Citometría de Flujo,
Inmunoglobulina E/sangre,
Recuento de Linfocitos,
Óxido Nítrico/sangre,
Otitis Media con Derrame/sangre,
Valores de Referencia,
Membrana Timpánica/metabolismo
Polat, Emre Can;
Besiroglu, Huseyin;
Ozcan, Levent;
Otunctemur, Alper;
Eruyar, Ahmet Tugrul;
Somay, Adnan;
Ozbay, Nurver;
Cekmen, Mustafa;
Eraldemir, Ceyla;
Ozbek, Emin.
ABSTRACT Introduction: We investigated whether Oltipraz (OPZ) attenuated renal fibrosis in a unilateral ureteral obstruction (UUO) rat model. Materials and Methods: We randomly divided 32 rats into four groups, each consisting of eight animals as follows: Rats in group 1 underwent a sham operation and ...
Cadherinas/sangre,
Modelos Animales de Enfermedad,
Fibrosis/tratamiento farmacológico,
Fibrosis/etiología,
Hidroxiprolina/sangre,
Inmunohistoquímica,
Enfermedades Renales/tratamiento farmacológico,
Enfermedades Renales/etiología,
Enfermedades Renales/patología,
Factor 2 Relacionado con NF-E2/uso terapéutico,
Óxido Nítrico/sangre,
Pirazinas/uso terapéutico,
Ratas Wistar,
Tionas,
Tiofenos,
Factor de Crecimiento Transformador beta1/sangre,
Obstrucción Ureteral/complicaciones,
Obstrucción Ureteral/tratamiento farmacológico,
Obstrucción Ureteral/patología
RESUMEN Objetivos. Evaluar los efectos de la administración de oxitocina en la conducción del parto en los niveles de malondialdehído (MDA), óxido nítrico (ON) y proteína S100B en el recién nacido. Material y Métodos. Se seleccionó a 80 gestantes a término sin patología obstétrica y fetal, fo...
Abstract Background: Obesity leads to a chronic inflammatory state, endothelial dysfunction and hypertension. Objective: To establish the time-course of events regarding inflammatory markers, endothelial dysfunction, systolic blood pressure (SBP) in obesity in only one experimental model. Methods: We ...
Presión Sanguínea/fisiología,
Citocinas/análisis,
Dieta Alta en Grasa/efectos adversos,
Modelos Animales de Enfermedad,
Endotelio Vascular/metabolismo,
Endotelio Vascular/fisiopatología,
Ensayo de Inmunoadsorción Enzimática,
Hipertensión/metabolismo,
Hipertensión/fisiopatología,
Inflamación/metabolismo,
Inflamación/fisiopatología,
Grasa Intraabdominal,
Peroxidación de Lípido,
Óxido Nítrico/sangre,
Obesidad/complicaciones,
Obesidad/metabolismo,
Obesidad/fisiopatología,
Distribución Aleatoria,
Ratas Wistar,
Factores de Tiempo
Abstract Purpose: To investigate thymoquinone, curcumin and a combination of these two drugs were effective or not at the growth of liver. Methods: Forty female Wistar-Albino rats distributed into five groups of eight rats each, control, thymoquinone, curcumin, and thymoquinone/curcumin groups. Pathol...
Antineoplásicos/farmacología,
Antioxidantes/farmacología,
Arginasa/sangre,
Benzoquinonas/farmacología,
Biomarcadores/sangre,
Proliferación Celular,
Ceruloplasmina/análisis,
Curcumina/farmacología,
Hepatectomía/métodos,
Antígeno Ki-67/análisis,
Hígado/patología,
Neoplasias Hepáticas/cirugía,
Regeneración Hepática/efectos de los fármacos,
Trasplante de Hígado,
Óxido Nítrico/sangre,
Ratas Wistar,
Activador de Tejido Plasminógeno/sangre
SUMMARY: Morphine is one of the naturally occurring phenanthrene alkaloids of opium that induces adverse effects on male reproductive system. Resveratrol is a phytoestrogen and antioxidant of red grape. The main goal is to investigate whether resveratrol could inhibit adverse effects of morphine on sperm...
SUMMARY: Diabetes mellitus is a common metabolic disease. There are many natural agents available to control and treat diabetes. Crab shell extract has antioxidant properties. The aim of present study was to investigate the effect of crab shell hydroalcoholic extract on blood glucose, liver enzymes, nitr...
SUMMARY: Morphine produces free radicals and cause apoptosis in some cell. Resveratrol (RSV) is a stilbenoid, a type of natural phenol, and a phytoalexin produced by several plants in response to injury. 48 male mice were randomly assigned to 8 groups. In this study, various doses of RSV (2, 8 and 20 mg/...
Summary Objective: Nitric oxide (NO), carbon monoxide (CO) and hydrogen sulfide (H2S) were endogenously-generated molecules gas. They owned important biological activity and participated in many pathophysiological processes. This study aimed to examine the levels of three gasotransmitters in the early p...