Background: Colorectal cancer (CRC) is the third most prevalent type of cancer worldwide, and is one of the major health problems in Asia, Africa, Europe, and America. The tumor antigens recently are of interesting indicators as diagnostic and prognostic tools, The aim of the present study is to detect t...
SUMMARY: Immunohistochemistry allows in situ detection of cell and extracellular components through specific antibodies. The objective was to compare the immunohistochemical expression patterns of the S-100, HMB-45 and MART-1 proteins for differential diagnosis of malignant melanoma and melanocytic nevus...
Neoplasias Cutáneas/diagnóstico,
Neoplasias Cutáneas/patología,
Melanoma/diagnóstico,
Melanoma/patología,
Nevo/diagnóstico,
Nevo/patología,
Inmunohistoquímica,
Diagnóstico Diferencial,
Biomarcadores de Tumor,
Complejo Antígeno-Anticuerpo,
Antígenos de Neoplasias,
Proteínas S100,
Antígeno MART-1
Abstract Background: Squamous cell carcinoma antigen (SCCA) is used as a prognostic marker for recurrence of squamous cell carcinoma in various sites, including head and neck. Studies suggest that its high serum levels are correlated to some clinical features, such as nodal metastasis. However, it is st...
ABSTRACT Background: The diagnostic value and suitability of prostate cancer antigen 3 (PCA3) for the detection of prostate cancer (PCa) have been inconsistent in previous studies. Thus, the aim of the present meta-analysis was performed to systematically evaluate the diagnostic value of PCA3 for PCa. ...
Resumen Los anticuerpos terapéuticos son proteínas recombinantes empleadas en el tratamiento del cáncer. Existe una nueva generación de anticuerpos monoclonales con actividad contra las células cancerosas, conocidos como anticuerpos conjugados a fármacos. Estas moléculas están integradas por tres...
ABSTRACT Objectives: To investigate whether Glasgow Prognostic Score has prognostic significance in patients with upper urinary urothelial carcinoma. Patients and methods: We retrospectively reviewed the clinical records of 74 patients with upper urinary urothelial carcinoma. We set the cut-off value f...
Antígenos de Neoplasias/sangre,
Biomarcadores de Tumor/sangre,
Proteína C-Reactiva/análisis,
Carcinoma/sangre,
Carcinoma/patología,
Estimación de Kaplan-Meier,
Queratina-19/sangre,
Persona de Mediana Edad,
Pronóstico,
Modelos de Riesgos Proporcionales,
Valores de Referencia,
Reproducibilidad de los Resultados,
Estudios Retrospectivos,
Sensibilidad y Especificidad,
Albúmina Sérica/análisis,
Estadísticas no Paramétricas,
Neoplasias Urológicas/sangre,
Neoplasias Urológicas/patología,
Urotelio/patología
OBJECTIVES: Osteosarcoma of the jaw (OSAJ) is fundamentally different in clinical practice from its peripheral counterparts. Studies are difficult to conduct due to low incidence rates. The primary aim of this study was to provide for the first time a comprehensive retrospective analysis of the treatment...
Anticuerpos Monoclonales/análisis,
Antígenos de Neoplasias/análisis,
Austria/epidemiología,
Biomarcadores/análisis,
Neoplasias Óseas/mortalidad,
Neoplasias Óseas/patología,
Neoplasias Óseas/terapia,
Inmunohistoquímica,
Osteosarcoma/mortalidad,
Osteosarcoma/patología,
Osteosarcoma/terapia,
Pronóstico,
Estudios Retrospectivos,
Tasa de Supervivencia
ABSTRACT Background: The association of prostate cancer antigen 3 (PCA3) polymorphism (SNP, rs544190G>A) with metastatic prostate cancer in European descent has been reported. Our aim of the current study was to re-validate the effect of PCA3 polymorphism on prostate cancer risk in an Eastern Chinese...
Antígenos de Neoplasias/genética,
Pueblo Asiatico/genética,
Estudios de Casos y Controles,
China,
Expresión Génica,
Estudios de Asociación Genética,
Genotipo,
Modelos Logísticos,
Clasificación del Tumor,
Estadificación de Neoplasias,
Polimorfismo de Nucleótido Simple/genética,
Neoplasias de la Próstata/etnología,
Neoplasias de la Próstata/genética,
Neoplasias de la Próstata/patología,
Medición de Riesgo/métodos,
Factores de Riesgo,
Fumar/efectos adversos
Adenocarcinoma/sangre,
Adenocarcinoma/diagnóstico,
Adenocarcinoma/economía,
Antígenos de Neoplasias/sangre,
Biomarcadores de Tumor/sangre,
Región del Caribe,
Análisis Costo-Beneficio,
Países en Desarrollo/economía,
Detección Precoz del Cáncer/economía,
América Latina,
Proteínas de Neoplasias/sangre,
Neoplasias de la Próstata/sangre,
Neoplasias de la Próstata/diagnóstico,
Neoplasias de la Próstata/economía,
Sensibilidad y Especificidad
The immunologic landscape of tumors has been continuously unveiled, providing a new look at the interactions between cancer cells and the immune system. Emerging tumor cells are constantly eliminated by the immune system, but some cells establish a long-term equilibrium phase leading to tumor immunoediti...
Antígenos de Neoplasias/análisis,
Vacunas contra el Cáncer/uso terapéutico,
Transformación Celular Neoplásica,
Terapia Combinada,
Terapia Genética,
Inmunoterapia/métodos,
Mutación,
Neoplasias/genética,
Neoplasias/inmunología,
Neoplasias/terapia,
Escape del Tumor/inmunología,
Microambiente Tumoral/inmunología
