Concerning the specificities of a longitudinal study, the trajectories of a subject's mean responses not always present a linear behavior, which calls for tools that take into account the non-linearity of individual trajectories and that describe them towards associat...
Ratones,
Trayectoria del Peso Corporal,
Trypanosoma cruzi/inmunología,
Pesos y Medidas Corporales,
Bioterápicos/antagonistas & inhibidores,
Pollos,
Suero/inmunología,
Trypanosoma cruzi/parasitología,
Enfermedad de Chagas/tratamiento farmacológico,
Antígenos de Protozoos/inmunología,
Anticuerpos Antiprotozoarios/inmunología,
Ensayo Clínico Controlado Aleatorio Veterinario,
Suero/parasitología
Germanó, María José;
Lozano, Esteban Sebastián;
Sanchez, María Victoria;
Bruna, Flavia Alejandra;
García-Bustos, María Fernanda;
Sosa Lochedino, Arianna Lourdes;
Salomón, María Cristina;
Fernandes, Ana Paula;
Mackern-Oberti, Juan Pablo;
Cargnelutti, Diego Esteban.
BACKGROUND Unfortunately, no any vaccine against leishmaniasis has been developed for human use. Therefore, a vaccine based on total Leishmania antigens could be a good and economic approach; and there are different methodologies to obtain these antigens. However, it is unknown whether the method to obt...
Abstract INTRODUCTION: Elimination of malaria in areas of interrupted transmission warrants careful case assessment to avoid the reintroduction of this disease. Occasional malaria cases are reported among visitors of the Atlantic Forest area of Brazil, while data on residents of this area are scarce. ...
Antígenos de Protozoos/inmunología,
Infecciones Asintomáticas/epidemiología,
Brasil/epidemiología,
Estudios Transversales,
ADN Protozoario/análisis,
Ensayo de Inmunoadsorción Enzimática,
Malaria Falciparum/diagnóstico,
Malaria Falciparum/epidemiología,
Malaria Falciparum/transmisión,
Malaria Vivax/diagnóstico,
Malaria Vivax/epidemiología,
Malaria Vivax/transmisión,
Reacción en Cadena de la Polimerasa
Costa, Monica Regina Farias;
Barcelos, Ana Luísa Rubert;
Camargo, Maria Angélica de;
Melo, Gisely Cardoso de;
Almeida, Anne Cristine;
Costa, Allyson Guimarães da;
Sousa, Jose Diego de Brito;
Melo, Marly Marques de;
Alecrim, Maria das Graças Costa;
Lacerda, Marcus Vinicius Guimarães de;
Monteiro, Wuelton Marcelo.
Abstract INTRODUCTION: Rapid diagnostic tests (RDTs) for detecting Plasmodium antigens have become increasingly common worldwide. We aimed to evaluate the accuracy of the Immuno-Rapid Malaria Pf/Pv RDT in detecting Plasmodium vivax infection compared to standard thick blood smear (TBS) under microscopy...
Abstract Background: Vimentin is a main structural protein of the cell, a component of intermediate cell filaments and immersed in cytoplasm. Vimentin is mimicked by some bacterial proteins and anti-vimentin antibodies occur in autoimmune cardiac disease, as rheumatic fever. In this work we studied vime...
Análisis de Varianza,
Anticuerpos Antiprotozoarios/análisis,
Anticuerpos Antiprotozoarios/inmunología,
Antígenos de Protozoos/análisis,
Antígenos de Protozoos/inmunología,
Células Cultivadas,
Enfermedad de Chagas/inmunología,
Ensayo de Inmunoadsorción Enzimática/métodos,
Técnica del Anticuerpo Fluorescente Indirecta/métodos,
Macaca mulatta,
Valores de Referencia,
Estadísticas no Paramétricas,
Trypanosoma cruzi/inmunología,
Vimentina/inmunología
Abstract INTRODUCTION: The production of the Montenegro antigen for skin test poses difficulties regarding quality control. Here, we propose that certain animal models reproducing a similar immune response to humans may be used in the quality control of Montenegro antigen production. METHODS: Fifteen C...
BACKGROUND The surface of infected red blood cells (iRBCs) has been widely investigated because of the molecular complexity and pathogenesis mechanisms involved. Asymptomatic individuals are important in the field because they can perpetuate transmission as natural reservoirs and present a challenge for ...
Anticuerpos Antiprotozoarios/genética,
Anticuerpos Antiprotozoarios/inmunología,
Antígenos de Protozoos/genética,
Antígenos de Protozoos/inmunología,
Infecciones Asintomáticas,
Western Blotting,
Electroforesis en Gel Bidimensional,
Membrana Eritrocítica/inmunología,
Membrana Eritrocítica/parasitología,
Espectrometría de Masas,
Plasmodium falciparum/genética,
Plasmodium falciparum/inmunología,
Proteómica
Duarte, Mariana Costa;
Lage, Daniela Pagliara;
Martins, Vívian Tamietti;
Chávez-Fumagalli, Miguel Angel;
Roatt, Bruno Mendes;
Menezes-Souza, Daniel;
Goulart, Luiz Ricardo;
Soto, Manuel;
Tavares, Carlos Alberto Pereira;
Coelho, Eduardo Antonio Ferraz.
Abstract: Visceral leishmaniasis (VL) is one of the most important tropical diseases worldwide. Although chemotherapy has been widely used to treat this disease, problems related to the development of parasite resistance and side effects associated with the compounds used have been noted. Hence, alternat...
ABSTRACT Visceral Leishmaniasis, also know as Kala-azar, is a parasitic tropical disease caused by protozoa of the genus Leishmania donovani. It is an endemic disease in many countries. It affects approximately 1,5 million people every year, and when associated with mal-nutrition and co-infection it may ...
Leishmaniasis Visceral/complicaciones,
Leishmaniasis Visceral/diagnóstico,
Leishmaniasis Visceral/tratamiento farmacológico,
Infecciones Parasitarias del Ojo/etiología,
Infecciones Parasitarias del Ojo/diagnóstico,
Infecciones Parasitarias del Ojo/tratamiento farmacológico,
Hemorragia Retiniana/etiología,
Hemorragia Retiniana/diagnóstico,
Hemorragia Retiniana/tratamiento farmacológico,
Pruebas Serológicas/métodos,
Antígenos de Protozoos/inmunología,
Anticuerpos Antiprotozoarios/sangre,
Proteínas Protozoarias,
Oftalmoscopía,
Anfotericina B/uso terapéutico,
Angiografía con Fluoresceína,
Hepatomegalia,
Esplenomegalia,
Pancitopenia
