Barreto-Vieira, Debora Ferreira;
da Silva, Marcos Alexandre Nunes;
Garcia, Cristiana Couto;
Miranda, Milene Dias;
Matos, Aline da Rocha;
Caetano, Braulia Costa;
Resende, Paola Cristina;
Motta, Fernando Couto;
Siqueira, Marilda Mendonça;
Girard-Dias, Wendell;
Archanjo, Bráulio Soares;
Barth, Ortrud Monika.
BACKGROUND The coronaviruses (CoVs) called the attention of the world for causing outbreaks of severe acute respiratory syndrome (SARS-CoV), in Asia in 2002-03, and respiratory disease in the Middle East (MERS-CoV), in 2012. In December 2019, yet again a new coronavirus (SARS-CoV-2) first identified in ...
Chlorocebus aethiops,
Efecto Citopatogénico Viral,
Vesículas Citoplasmáticas/virología,
Endocitosis,
Retículo Endoplásmico/virología,
Microscopía Electrónica de Transmisión,
Nucleocápside,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Reacción en Cadena de la Polimerasa de Transcriptasa Inversa,
SARS-CoV-2/fisiología,
Células Vero/virología,
Internalización del Virus
BACKGROUND The impact of arbovirus cocirculation in Brazil is unknown. Dengue virus (DENV) reinfection may result in more intense viraemia or immunopathology, leading to more severe disease. The Zika virus (ZIKV) epidemic in the Americas provided pathogenicity evidence that had not been previously obser...
Araujo, Danielle Bastos;
Machado, Rafael Rahal Guaragna;
Amgarten, Deyvid Emanuel;
Malta, Fernanda de Mello;
de Araujo, Gabriel Guarany;
Monteiro, Cairo Oliveira;
Candido, Erika Donizetti;
Soares, Camila Pereira;
de Menezes, Fernando Gatti;
Pires, Ana Carolina Cornachioni;
Santana, Rúbia Anita Ferraz;
Viana, Amanda de Oliveira;
Dorlass, Erick;
Thomazelli, Luciano;
Ferreira, Luis Carlos de Sousa;
Botosso, Viviane Fongaro;
Carvalho, Cristiane Rodrigues Guzzo;
Oliveira, Danielle Bruna Leal;
Pinho, João Renato Rebello;
Durigon, Edison Luiz.
BACKGROUND Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was confirmed in Brazil in February 2020, the first cases were followed by an increase in the number of cases throughout the country, resulting in an important public health crisis that requires fast and coordinated responses. OBJE...
Abstract INTRODUCTION: Insect cell cultures play an essential role in understanding arboviral replication. However, the replicative efficiency of some of these viruses such as dengue (DENV), yellow fever (YFV), and chikungunya (CHIKV) in a new cellular substrate (Lulo) and in the other two recognized ce...
Strottmann, Daisy Maria;
Zanluca, Camila;
Mosimann, Ana Luiza Pamplona;
Koishi, Andrea C;
Auwerter, Nathalia Cavalheiro;
Faoro, Helisson;
Cataneo, Allan Henrique Depieri;
Kuczera, Diogo;
Wowk, Pryscilla Fanini;
Bordignon, Juliano;
Duarte dos Santos, Claudia Nunes.
BACKGROUND Zika virus (ZIKV) infections reported in recent epidemics have been linked to clinical complications that had never been associated with ZIKV before. Adaptive mutations could have contributed to the successful emergence of ZIKV as a global health threat to a nonimmune population. However, the...
Aedes/virología,
Brasil,
Chlorocebus aethiops,
Ratones Endogámicos BALB C,
Filogenia,
Células Vero,
Carga Viral,
Cultivo de Virus,
Replicación Viral,
Virus Zika/genética,
Infección por el Virus Zika/virología
Cota, Betania Barros;
Tunes, Luiza Guimarães;
Maia, Daniela Nabak Bueno;
Ramos, Jonas Pereira;
Oliveira, Djalma Menezes de;
Kohlhoff, Markus;
Alves, Tânia Maria de Almeida;
Souza-Fagundes, Elaine Maria;
Campos, Fernanda Fraga;
Zani, Carlos Leomar.
BACKGROUND In a screen of extracts from plants and fungi to detect antileishmanial activity, we found that the ethyl acetate extract of the fungus Nectria pseudotrichia, isolated from the tree Caesalpinia echinata (Brazilwood), is a promising source of bioactive compounds. OBJECTIVES The aims of this st...
BACKGROUND Trypanosoma cruzi is a protozoan parasite and an etiological agent of Chagas disease. There is a wide variability in the clinical outcome of its infection, ranging from asymptomatic individuals to those with chronic fatal mega syndromes. Both parasite and host factors, as well as their interpl...
ABSTRACT Clostridium perfringens is the causative agent for necrotic enteritis. It secretes the major virulence factors, and α- and NetB-toxins that are responsible for intestinal lesions. The TpeL toxin affects cell morphology by producing myonecrosis, but its role in the pathogenesis of necrotic e...
Adhesión Bacteriana,
Proteínas Bacterianas/genética,
Proteínas Bacterianas/metabolismo,
Chlorocebus aethiops,
Infecciones por Clostridium/microbiología,
Infecciones por Clostridium/veterinaria,
Clostridium perfringens/genética,
Clostridium perfringens/aislamiento & purificación,
Clostridium perfringens/fisiología,
Células Epiteliales/microbiología,
Enfermedades de las Aves de Corral/microbiología,
Células Vero,
Pollos
ABSTRACT With the aim of introducing permanent prostheses with main properties equivalent to cortical human bone, Ti-diamond composites were processed through powder metallurgy. Grade 1 titanium and mixtures of Ti powder with 2%, 5% and 10 wt% diamond were compacted at 100MPa, and then sintered at 1250°...
BACKGROUND Dengue is considered one of the world’s most important mosquito-borne diseases. MicroRNAs (miRNAs) are small non-coding single-stranded RNAs that play an important role in the regulation of gene expression in eukaryotes. Although miRNAs possess antiviral activity against many mammalian-...
Western Blotting,
Chlorocebus aethiops,
Biología Computacional,
Virus del Dengue/genética,
Virus del Dengue/fisiología,
Citometría de Flujo,
Regulación de la Expresión Génica/genética,
MicroARNs/metabolismo,
Reacción en Cadena de la Polimerasa,
Replicación Viral/genética,
Replicación Viral/fisiología,
Regiones no Traducidas,
Regiones no Traducidas/fisiología
