Abstract The present study was conducted to evaluate the chemical composition, antioxidant activity and hypoglycemic effects of whole kumquat (Ku) powder in diabetic rats fed a high-fat-high-cholesterol (HFHC) diet. The antioxidant activities were evaluated using stable 1,1-diphenyl 2-picrylhydrazyl (DPP...
The genus Pouteria has been studied because it presents various activities, among which is its anti-inflammatory potential. The effects of Pouteria ramiflora Carbopol gel on the healing of skin wounds in diabetic rats were evaluated by microscopic imaging. Streptozotocin was administered intraperitoneall...
Resumo Fundamentos A L-carnitina (LC) tem muitos efeitos benéficos em animais diabéticos e humanos, mas seu efeito regulatório sobre a quemerina como uma citocina inflamatória e seu receptor no estado diabético são desconhecidos. Objetivos O presente estudo teve como objetivo investigar o efeit...
BACKGROUND Diabetes is a metabolic disorder caused by defects in insulin production and activity. During disease progression, changes in lipid peroxidation cause structural modifications via production of free radicals. Fangchinoline is a well-known alkaloid present in Stephaniae tetrandrine S. Moore, wh...
SUMMARY: Diabetes mellitus can lead to structural disorders in the brain. One of the most common complications of diabetes, diabetic neuropathy is associated with central nervous system disorders. Aloe vera has anti-diabetic, antioxidant, and neuroprotective effects. This study was designed to evaluate t...
Diabetes Mellitus Experimental/tratamiento farmacológico,
Aloe/química,
Extractos Vegetales/administración & dosificación,
Extractos Vegetales/farmacología,
Hipocampo/efectos de los fármacos,
Factor de Crecimiento Nervioso/efectos de los fármacos,
Administración Oral,
Proteínas Tirosina Quinasas Receptoras/efectos de los fármacos,
Proteínas Tirosina Quinasas Receptoras/genética,
Factor de Crecimiento Nervioso/genética,
Receptor de Factor de Crecimiento Nervioso/efectos de los fármacos,
Receptor de Factor de Crecimiento Nervioso/genética,
Ratas Wistar,
Reacción en Cadena en Tiempo Real de la Polimerasa
ABSTRACT Purpose The present study explored the influence of liraglutide on remote preconditioning-mediated cardioprotection in diabetes mellitus along with the role of nuclear factor erythroid 2-related factor 2 (Nrf2), hypoxia inducible factor (HIF-1α) and hydrogen sulfide (H2S). Methods Strepto...
Abstract The present work aims to investigate the antiparasitic and the immunomodulating effects of nitazoxanide (NTZ) and ivermectin (IVC) alone or combined together or combined with selenium (Se), on Cryptosporidium infection in diabetic mice. The results revealed that the combined NTZ and IVC therapy ...
Medeiros, Scheila;
Maia, Thayná Patachini;
Lima, Aline Barbosa;
Pscheidt, Luana Carla;
Delmonego, Larissa;
Vincenzi, Karine Louize;
Custodio, Bruna Vanzin;
Dal Magro, Débora Delwing;
Barauna, Sara Cristiane;
Alberton, Michele Debiasi;
Pereira, Eduardo Manoel;
Delwing-de Lima, Daniela.
We investigated the effects of dichloromethane extract (DME) from Myrcia splendenson alterations caused by type 2 diabetes in the blood and kidney of rats, in order to reduce side effects caused by synthetic drugs. Rats received streptozotocin (60 mg/kg),15 minutes after nicotinamide (120 mg/kg) or water...
Myrtaceae/química,
Diabetes Mellitus Experimental/tratamiento farmacológico,
Extractos Vegetales/administración & dosificación,
Cloruro de Metileno/administración & dosificación,
Hipolipemiantes/administración & dosificación,
Hipoglucemiantes/administración & dosificación,
Antioxidantes/administración & dosificación,
Extractos Vegetales/química,
Compuestos Fenólicos/análisis,
Estrés Oxidativo/efectos de los fármacos,
Cromatografía Líquida de Alta Presión,
Espectrometría de Masa por Ionización de Electrospray,
Ratas Wistar,
Glucemia/efectos de los fármacos,
Estreptozocina
SUMMARY: Herbal extracts used for treatment of diabetes has focused mostly on the hypoglycaemic and anti-oxidant property.There are no studies which focused on its effect on dendritic architecture of pyramidal neurons of hippocampus caused by diabetes. This study was taken up to explore the effect of adm...
SUMMARY: The aim of this study is to investigate the effects of Protocatechuic acid and Corchorus olitorius on streptozotocin (STZ) induced diabetic rat testis tissue. Randomly selected Wistar Albino rats were divided into five groups as; Diabetes Mellitus, Diabetes Mellitus treated with Corchorus Olitor...
