Alcohol abuse has impacts on public health worldwide. Conservative treatment to
achieve abstinence consists of detoxification combined with psychotherapy and the
use of drugs, but it is estimated that only half of the individuals achieve long-term
abstinence with the available treatments. In this sense, ...
Deep brain stimulation has become an option for advanced Parkinson’s disease
treatment since the 1990s, but the first reports are from Benabid’s team, a French
neurosurgeon, in the 1980s. The subthalamic nucleus (STN), more specifically its
dorsolateral portion, is the most commonly stimulated brain ...
Núcleo Subtalámico/diagnóstico por imagen,
Núcleo Subtalámico/cirugía,
Cráneo/anatomía & histología,
Estimulación Encefálica Profunda/métodos,
Procesamiento de Imagen Asistido por Computador,
Espectroscopía de Resonancia Magnética/métodos,
Procedimientos Neuroquirúrgicos/métodos,
Enfermedad de Parkinson/terapia,
Núcleo Rojo,
Hipotálamo Posterior,
Núcleo Interpeduncular,
Electrodos Implantados
Silva de Magalhães, Marcelo José;
dos Reis, Claudiojanes;
Rabelo da Silva Sousa, Juliana;
Souza Marques, Victória;
Cardoso Gonçalves, Tayná;
Vieira Ribeiro, Iara Cristina;
Silveira Cardoso, Leide Daiana;
Caribé Crosland Guimarães, Victor;
de Souza Marques, Frederico Gustavo;
Dias Pereira, Sarah.
Discovered in 1865 by Jules Bernard Luys, the subthalamic nucleus is a set of small
nuclei located in the diencephalon, inferior to the thalamus and superior to the
substantia nigra, that can be visualized in a posterior coronal section. Histologically, it
consists of neurons compactly distributed and fi...
INTRODUCCIÓN: La estimulación cerebral profunda (DBS) se ha propuesto como una alternativa terapéutica para el manejo de la depresión resistente al tratamiento (DRT). Sin embargo, existen múltiples blancos para neuroestimulación y se desconoce el punto neuroanatómico óptimo en esta patología. Co...
Borrione, Lucas;
Bellini, Helena;
Razza, Lais Boralli;
Avila, Ana G.;
Baeken, Chris;
Brem, Anna-Katharine;
Busatto, Geraldo;
Carvalho, Andre F.;
Chekroud, Adam;
Daskalakis, Zafiris J.;
Deng, Zhi-De;
Downar, Jonathan;
Gattaz, Wagner;
Loo, Colleen;
Lotufo, Paulo A.;
Martin, Maria da Graça M.;
McClintock, Shawn M.;
OShea, Jacinta;
Padberg, Frank;
Passos, Ives C.;
Salum, Giovanni A.;
Vanderhasselt, Marie-Anne;
Fraguas, Renerio;
Benseñor, Isabela;
Valiengo, Leandro;
Brunoni, Andre R..
Current first-line treatments for major depressive disorder (MDD) include pharmacotherapy and cognitive-behavioral therapy. However, one-third of depressed patients do not achieve remission after multiple medication trials, and psychotherapy can be costly and time-consuming. Although non-implantable neur...
Substance-related disorders are psychiatric conditions that have a worldwide impact.
Their multifactorial cycle has been treated pharmacologically and with therapeutic
support. However, high refractoriness rates and difficulty to control relapses are among
the pitfalls associated with these disorders. Th...
Objective: Parkinson's disease (PD) is often accompanied by stigma, which could contribute to a worse prognosis. The objective of this study is to identify the variables associated with stigma in PD patients who are candidates for deep brain stimulation (DBS). Methods: We investigated sociodemographic a...
Actividades Cotidianas/psicología,
Estudios Transversales,
Estimulación Encefálica Profunda/métodos,
Persona de Mediana Edad,
Enfermedad de Parkinson/psicología,
Enfermedad de Parkinson/terapia,
Calidad de Vida/psicología,
Índice de Severidad de la Enfermedad,
Estigma Social,
Encuestas y Cuestionarios,
Resultado del Tratamiento
Introduction: Deep brain stimulation (DBS) is a standard surgical procedure for the treatment of advanced Parkinson Disease (PD) with motor complications that cannot be adequately managed by medical treatment. Currently available literature can guide physicians on basic aspects of...
Depression is the leading cause of disability worldwide, and it is related to high suicide
rates. Furthermore, a great number of patients do not respond to any of the available
treatments. Deep brain stimulation (DBS), a versatile technology with expanding
indications, is considered a potential treatment...
