Cancer is an abnormal and uncontrolled growth of cells that spreads through cell division. There are different types of medicines available to treat cancers, but no drug is found to be fully effective and safe for humans. The major problem involved in the cancer treatments is the toxicity of the establi...
Cordeiro, M F;
Nunes, T R S;
Bezerra, F G;
Damasco, P K M;
Silva, W A V;
Ferreira, M R A;
Magalhães, O M C;
Soares, L A L;
Cavalcanti, I M F;
Pitta, M G R;
Rêgo, M J B M.
Plectranthus barbatus Andrews (Lamiaceae) is widely distributed in the world and has a range of popular therapeutic indications. This work aimed to evaluate the phytochemical characterization of two leaf extracts of P. barbatus, and their antimicrobial, antineoplastic and immunomodulatory potential. Afte...
Plants possess a renewable source of metabolites with enormous chemical structural diversity, which may have potential therapeutic relevance. Furthermore, this chemical diversity favors the possibility of finding new and different chemical constituents with antimicrobial, antioxidant and anti-tumor activ...
Silva, K B;
Pinheiro, C T S;
Soares, C R M;
Souza, M A;
Matos-Rocha, T J;
Fonseca, S A;
Pavão, J M S J;
Costa, J G;
Pires, L L S;
Santos, A F.
Abstract The objective of this work was to perform the phytochemical characterization, to determine total phenols, antioxidant (AAO%) and antimicrobial potential of the ethanolic extracts of carambola. The phytochemical study was carried out through a qualitative analysis of the chemical constituents and...
BACKGROUND: Leaves of the natural plant lotus are used in traditional Chinese medicine and tea production. They are rich in flavonoids. METHODS: In this study, lotus leaf flavonoids (LLF) were applied to human lung cancer A549 cells and human small cell lung cancer cells H446 in vitro to verify the effec...
Apoptosis/efectos de los fármacos,
Flavonoides/farmacología,
Lotus/química,
Neoplasias Pulmonares/patología,
Especies Reactivas de Oxígeno/metabolismo,
Proteínas Quinasas p38 Activadas por Mitógenos/metabolismo,
Células A549,
Proliferación Celular,
Neoplasias Pulmonares/tratamiento farmacológico,
Fitoquímicos/farmacología,
Hojas de la Planta/química,
Transducción de Señal/efectos de los fármacos
HIGHLIGHTS Isolate, fractionate and characterize extracts obtained from soursop leaves. Use of emerging green technologies such as microwave-ultrasound hybridization. The extracts contain kaempferol, procyanidins, catechin, and quercetin. The total ethanolic extract demonstrates cytotoxic effect on...
Abstract In vitro and screen house experiments were conducted to investigate the effectiveness of thirteen phytochemicals from Artemisia elegantissimia and A. incisa on root knot nematode, Meloidogyne incognita in tomato (Lycopersicon esculentum L.) cv. Rio Grande. A positive control (Carbofuran) and neg...
Abstract In this study, it is aimed to investigate the effects of Moringa oleifera and Sorbus domestica plant extracts on bacterial disease agents Yersinia ruckeri in aquaculture. Morphological and biochemical properties of 2 different Y. ruckeri isolates were determined. Then, Real-Time PCR analysis and...
Silva, E A J;
Estevam, E B B;
Silva, T S;
Nicolella, H D;
Furtado, R A;
Alves, C C F;
Souchie, E L;
Martins, C H G;
Tavares, D C;
Barbosa, L C A;
Miranda, M L D.
Abstract This study evaluated the antibacterial and antiproliferative activities of the essential oil of Psidium guajava leaves (PG-EO), traditionally used in folk medicine. The essential oil was obtained from fresh leaves by hydrodistillation, using a modified Clevenger apparatus. The major PG-EO chemi...
Antibacterianos/farmacología,
Azulenos/farmacología,
Proliferación Celular/efectos de los fármacos,
Cromatografía de Gases y Espectrometría de Masas,
Pruebas de Sensibilidad Microbiana,
Sesquiterpenos Monocíclicos,
Aceites Volátiles/farmacología,
Fitoquímicos/farmacología,
Extractos Vegetales/farmacología,
Hojas de la Planta,
Sesquiterpenos Policíclicos,
Psidium,
Sesquiterpenos/farmacología
Abstract This study aimed to evaluate the in vitro antibacterial activity of the phytochemicals thymol, linalool, and citronellol against Streptococcus mutans, Streptococcus salivarius and Streptococcus oralis. Disk diffusion screening on solid medium and measurement of the diameter of the bacterial grow...
