O câncer de pele pode ser classificado como não melanoma e melanoma. O melanoma apresenta baixa incidência entre os cânceres de pele, porém é a forma mais letal e é considerado um dos tipos mais resistentes ao tratamento. Devido à infiltração de células malignas nos tecidos, vasos linfáticos ...
Abstract Introduction: In this study, we aimed to detect the cytokine that is involved in the early stage of chronic kidney disease and associated with cardiovascular disease. Methods: We included 50 patients who were diagnosed with predialytic chronic kidney disease and 30 healthy pediatric patients i...
In this study, it was aimed to determine the antioxidant and anticancer activities of Sideritis perfoliata methanolic extract (SPE) on cervical cancer cells (HeLa). Different doses (25, 50,100 and 200 μg/mL) of SPE were used to determine proliferation of HeLa cells by 3-[4,5-dimethylthiazol-2-yl]-2,5-di...
Neoplasias del Cuello Uterino,
Sideritis/química,
Proliferación Celular/efectos de los fármacos,
Apoptosis/efectos de los fármacos,
Antioxidantes/administración & dosificación,
Extractos Vegetales/administración & dosificación,
Antineoplásicos,
Interleucina-8/análisis,
Interleucina-6/análisis,
Extractos Vegetales/química,
Antioxidantes/química,
Fenoles/análisis,
Supervivencia Celular,
Cromatografía de Gases y Espectrometría de Masas
Helicobacter pylori (H. pylori) induces an intense inflammatory response, mediated by proinflammatory cytokines, including interleukin (IL)-6 and its membrane receptor (IL-6R), which activates important signaling pathways in the development of gastric disease and cancer. We investigated the gene and prot...
This study aimed to evaluate changes in beige adipocytes at different times of melatonin administration, in the morning (ZT01) or in the evening (ZT11), at 30 mg/kg daily by gavage for 7 weeks or continuously with drinking water in the term of high-calorie diet-induced obesity (HCD). Melatonin received a...
Abstract Background: Acute coronary syndrome (ACS) is a cardiovascular disease caused by obstruction of coronary arteries by atheromatous plaque. Susceptibility to this disease may be related to genetic variations, such as single nucleotide polymorphisms (SNPs). Objective: In this study, we evaluated t...
Olano, Carolina;
López, Virginia;
Freire, Teresa;
Rodríguez, Ximena;
Pontet, Yessica;
Alemán, Alicia;
Rodríguez, Natalia;
Rovira, Laura;
Trucco, Elena;
Osinaga, Eduardo;
Cohen, Henry;
Quigley, Eamonn MM.
ABSTRACT Background: Evidence indicates that low-grade inflammation can alter gastrointestinal motor and sensory function and might contribute to the genesis of symptoms in IBS. Objective: To examine relationships between IBS, disease antibodies and cytokine titers in celiac patients and a control gr...
ABSTRACT BACKGROUND: The role of -251A>T polymorphism in the anti-inflammatory cytokine interleukin-8 (IL-8) gene in gastric cancer was intensively evaluated, but the results of these studies were inconsistent. OBJECTIVE: Therefore, we performed a meta-analysis to provide a comprehensive data on t...
Abstract Brain tumors are one of the most common causes of cancer-related deaths around the world. Angiogenesis is critical in high-grade malignant gliomas, such as glioblastoma multiforme. Objective: The aim of this study is to comparatively analyze the angiogenesis-related genes, namely VEGFA, VEGFB,...
Neoplasias Encefálicas/genética,
Carcinogénesis/genética,
Expresión Génica,
Glioblastoma/genética,
Glioblastoma/patología,
Glioma/genética,
Glioma/patología,
Interleucina-8/análisis,
Neovascularización Patológica/genética,
Mutación Puntual/genética,
Receptores de Interleucina-8A/análisis,
Receptores de Interleucina-8B/análisis,
Valores de Referencia,
Factor A de Crecimiento Endotelial Vascular/análisis,
Factor B de Crecimiento Endotelial Vascular/análisis,
Receptor 2 de Factores de Crecimiento Endotelial Vascular/análisis
Abstract We sought to compare the characteristics and clinical significance of neutrophil extracellular traps in gingival samples from patients with periodontitis and those with gingivitis. The clinical indexes of gingival samples from patients with periodontitis and gingivitis were measured; the express...
Actinas/análisis,
Western Blotting,
Estudios de Casos y Controles,
Electroforesis en Gel de Agar,
Trampas Extracelulares,
Gingivitis/patología,
Interleucina-8/análisis,
Metaloproteinasa 9 de la Matriz/análisis,
Persona de Mediana Edad,
Neutrófilos/patología,
Índice Periodontal,
Periodontitis/patología,
ARN/análisis,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Valores de Referencia,
Receptor Toll-Like 8/análisis,
Factor de Necrosis Tumoral alfa/análisis
