SUMMARY: Magnolia bark extract supplementation has an anti-oxidative role in mammalians. However, its role in physiological aged-associated heart insufficiency is not known yet. Therefore, we investigated the effects of a magnolia bark complex, including magnolol and honokiol components (MAHOC), in elder...
Objective: This in vitro study evaluated the effect of neolignan-containing solutions on dentin biomodification previously applied to the bonding procedure in adhesive restorations. Material and Methods: Neolignans, dehydrodieugenol B–CP1 and dehydrodieugenol B methyl ether–CP2, were iso...
Abstract A phytochemical study of Tecoma genus (Bignoniaceae) was accomplished by antitumor activity of ethanolic extracts. Species of this genus are composed of small shrubs often used as ornamental plants. The Tecoma stans species is used in folk medicine for different purposes. Recent work shows in vi...
Drimys winteri JR et G. Forster var chilensis (DC) A. is a tree native to central and southern Chile. Also it found in part of Argentina. It is abundant in wet swampy localities from sea level to an altitude of 1700 m. This tree is sacred for the Mapuche culture; it is used in folk medicine in such as...
Piper kadsura (Choisy) Ohwi which belongs to the family Piperaceae, is a well-known medicinal plant possessing high medicinal and various therapeutic properties. It is widely used in traditional Chinese medicine for the treatment of asthma and rheumatic arthritis. Numerous studies on this species have al...
Piper/química,
Antiinflamatorios/química,
Antiinflamatorios/farmacología,
Lignanos/análisis,
Alcaloides/análisis,
Plantas Medicinales,
Aceites Volátiles/química,
Fitoquímicos/análisis,
Piperaceae/química,
Medicina Tradicional China,
Kadsura
Malignant melanoma (MM) is one of the malignant tumors with highly metastatic and aggressive biological actions. Schizandrin A (SchA) is a bioactive lignin compound with strong anti-oxidant and anti-aging properties, which is stable at room temperature and is often stored in a cool dry place. Hence, we i...
Apoptosis/efectos de los fármacos,
Western Blotting,
Línea Celular Tumoral,
Movimiento Celular/efectos de los fármacos,
Proliferación Celular/efectos de los fármacos,
Ciclooctanos/farmacología,
Regulación hacia Abajo/efectos de los fármacos,
Regulación Neoplásica de la Expresión Génica/efectos de los fármacos,
Lignanos/farmacología,
Melanoma/patología,
MicroARNs/metabolismo,
Compuestos Policíclicos/farmacología,
ARN Largo no Codificante,
Reacción en Cadena en Tiempo Real de la Polimerasa,
Transducción de Señal/efectos de los fármacos
The therapeutic arsenal for the treatment of Leishmaniasis is limited and includes toxic compounds (antimonials, amphotericin B, pentamidine and miltefosine). Given these aspects, the search for new compounds based on floristic biodiversity is crucial. In the present work, we report the isolation, charac...
Abstract In this study, the potential antileukemic activity of grandisin, a lignan extracted from Piper solmsianum, was evaluated against the leukemic line K562. The cytotoxicity of grandisin (0.018 to 2.365 µM) was evaluated in K562 and normal peripheral blood lymphocytes by Trypan Blue Exclusion and M...
Ascosphaera apis is a bee pathogen that causes bee larvae infection disease, to which treatment is not yet well investigated. The aim of this study was to investigate antifungal susceptibility in vitro against A. apis and to identify a new antifungal agent for this pathogen through minimal inhibitory con...
Antifúngicos/farmacología,
Ascomicetos/efectos de los fármacos,
Abejas/microbiología,
Western Blotting,
Sinergismo Farmacológico,
Formazáns,
Larva/efectos de los fármacos,
Larva/microbiología,
Larva/patogenicidad,
Lignanos/farmacología,
Pruebas de Sensibilidad Microbiana,
Proteínas Quinasas Activadas por Mitógenos/análisis,
Proteínas Quinasas Activadas por Mitógenos/efectos de los fármacos,
Micosis/tratamiento farmacológico,
Proteínas de Saccharomyces cerevisiae/análisis,
Proteínas de Saccharomyces cerevisiae/efectos de los fármacos,
Sales de Tetrazolio,
Factores de Tiempo
Sesamin is a major lignan constituent of sesame seed and considered as a key factor in a number of beneficial effects on human health. Sesame leaves intake improve and increase epididymal spermatocytes reserve in adult male sprague dawley rat. The present study was aimed to investigate the effects of con...
