A quimioprevenção do câncer refere-se ao uso de compostos naturais ou sintéticos para prevenir o desenvolvimento das neoplasias antes do estabelecimento da malignidade. O ácido butirico (AB) atua como um potente quimiopreventivo na hepatocarcinogênese, reduzindo o número e o tamanho de lesões pr...
Lipase hypersecretion syndrome (LHS) is a rare paraneoplastic syndrome, associated with acinar cell carcinoma of the pancreas (ACCP) in 10% to 15% of patients. Clinically, LHS manifests itself with the appearance of subcutaneous fibrocystic nodules, associated with trophic changes in the overlying skin, ...
Enzymes of the archaea living in extreme environments are resistant to the challenging conditions. Lipase is among the important enzymes used in the industry and agriculture. In this study, the extracellular lipase from extremely halophilic archaeon Halolamina sp. was characterized for the first time. Op...
Surian, Cesar Rodrigo de Souza;
Surian, Soraya Regina Sacco;
Carneiro, Christofe;
Perosa, Fernanda Felicetti;
Horn, Vitor Waldir;
Fronza, Nei;
Bonassi, Daniele Elisa;
Peripolli, Vanessa;
Santarosa, Bianca Paola;
Gomes, Teane Milagres Augusto;
Mendes, Ricardo Evandro.
Eurytrema coelomaticum is a trematode reported in the pancreatic ducts of ruminants. It is conjectured that may cause disorders in the pancreas, as well as digestive and metabolic processes dependent on them. This study, determined if there is an impairment of exocrine pancreatic function, and correlated...
BACKGROUND The extracellular expression of enzymes in a secretion host such as Bacillus subtilis is a useful strategy in reducing the cost of downstream processing of industrial enzymes. Here, we present the first report of the successful extracellular expression in Bacillus subtilis WB800 of Geobacillus...
Gatto, Larissa Junqueira;
Oliveira, Gustavo Rezende Bellei de;
Rech, Katlin Suellen;
Moura, Paula Francislaine;
Gribner, Caroline;
Merino, Francis José Zortéa;
Ávila, Suelen;
Dias, Josiane de Fatima Gaspari;
Miguel, Obdulio Gomes;
Miguel, Marilis Dallarmi.
Several species of the Myrcia genus have been used in folk medicine to treat diabetes. Therefore, the aim of this work was to investigate the inhibitory activity of α-glucosidase and pancreatic lipase in the crude extract (EBF) and in the ethyl acetate fraction (FFA) of Myrcia hatschbachii, as well as t...
Myrtaceae/química,
Antioxidantes/farmacología,
Inhibidores de Glicósido Hidrolasas/farmacología,
Lipasa/efectos de los fármacos,
Páncreas/enzimología,
Extractos Vegetales/farmacología,
Extractos Vegetales/toxicidad,
Ácido Gálico,
Ácido Elágico,
Extractos Vegetales/química,
Antioxidantes/química,
Fenoles/análisis,
Difracción de Rayos X,
Depuradores de Radicales Libres,
Técnicas In Vitro,
Mezclas Complejas
A ansa pancreática é uma variação anatômica rara dos ductos
pancreáticos. Consiste numa comunicação entre o ducto pancreático principal (Wirsung) e o ducto pancreático acessório
(Santorini). Recentemente, estudos têm demonstrado estar essa
variação anatômica implicada como fator predisp...
Conductos Pancreáticos/diagnóstico por imagen,
Pancreatitis/diagnóstico por imagen,
Conductos Pancreáticos/anomalías,
Ictiosis Vulgar/diagnóstico,
Pancreatitis/sangre,
Amilasas/sangre,
Lipasa/sangre,
Proteína C-Reactiva/análisis,
Ultrasonografía,
Conductos Biliares Extrahepáticos/patología,
Tomografía Computarizada por Rayos X,
Pancreatitis/etiología,
Pancreatitis Aguda Necrotizante/diagnóstico por imagen,
Pancreatitis Aguda Necrotizante/etiología,
Pancreatitis/complicaciones,
Espectroscopía de Resonancia Magnética,
Seudoquiste Pancreático/diagnóstico por imagen
Introducción: La bioquímica, como ciencia particular dentro de las ciencias médicas, ha tenido un gran desarrollo. Las enzimas lipasas se obtienen de organismos vivos que abundan en la naturaleza y han sido utilizadas en la producción de alimentos, jabones, detergentes, aceites y otros productos ind...
BACKGROUND: Liquid wax esters are widely used in cosmetic as well as pharmaceutical and other industries. The demand of organic and natural products is increasing nowadays. Coconut oil contains benefit fatty acids and has been mainly used for oil-based and moisturizer products. Liquid wax esters from coc...
