Resumen Los síndromes esclerodermiformes suelen imitar muy bien una esclerosis sistémica progresiva, y es la presencia de ampollas cutáneas en áreas fotoexpuestas con hiperpigmentación los datos diferenciales para diagnosticar una porfiria. Presentamos el caso de un varón de 48 años con fotosensib...
Abstract: A 63-year-old black female patient with blisters and exulcerations on the face, neck, upper limbs, and subsequent evolution with hypochromic sclerotic areas and alopecia, is reported. Chronic hepatitis C and presence of high levels of porphyrins in urine were demonstrated. There was complete re...
Alopecia/etiología,
Hepatitis C Crónica/complicaciones,
Hepatitis C Crónica/patología,
Porfiria Cutánea Tardía/etiología,
Porfiria Cutánea Tardía/patología,
Esclerodermia Localizada/etiología,
Hepatitis C Crónica/terapia,
Porfiria Cutánea Tardía/terapia,
Esclerodermia Localizada/patología,
Esclerodermia Localizada/terapia,
Resultado del Tratamiento
ABSTRACT Introduction: Pseudoporphyria is a rare photodermatosis with characteristics similar to those of porphyria cutanea tarda, without, however, presenting abnormalities in porphyrin metabolism. Its etiology is related to chronic kidney disease, ultraviolet radiation and certain medications. The aim...
Porphyria cutanea tarda (PCT) is the most common type of porphyria: it is characterized by blistering lesions, erosions and crusts on the back of the hands, associated with photosensitivity and facial hypertrichosis. It is produced by acquired or hereditary deficiency of the enzyme UROD, fifth enzyme in ...
Abstract: Porphyria cutanea tarda has a complex etiology with genetic factors not completely elucidated. The miscegenation of the Brazilian population has important implications in the predisposition to diseases. There are no studies concerning the genetic ancestry of patients with porphyria cutanea tard...
Espinoza-Ríos, Jorge;
Valenzuela Granados, Vanessa;
Ojeda Cisneros, Manuel;
Gálvez Canseco, Aldo;
Ramos Aguilar, Cesar;
Raymundo Villalva, Brunella;
Aguilar Sánchez, Victor;
Pinto Valdivia, José;
Huerta-Mercado Tenorio, Jorge;
Bussalleu Rivera, Alejandro.
Se presenta el caso de un paciente varón de 56 años quien es evaluado por presentar a nivel del dorso de ambas manos cicatrices hiperpigmentadas e hipopigmentadas, asociadas a quistes de milia. Se le realizó estudios del metabolismo de las porfirinas y biopsia cutánea de las lesiones los cuales resul...
Hepatitis C Crónica/complicaciones,
Porfiria Cutánea Tardía/etiología,
Antivirales/uso terapéutico,
Biopsia,
Quimioterapia Combinada,
Deformidades Adquiridas de la Mano/etiología,
Deformidades Adquiridas de la Mano/patología,
Hepatitis C Crónica/diagnóstico,
Hepatitis C Crónica/tratamiento farmacológico,
Interferones/uso terapéutico,
Ribavirina/uso terapéutico
Abstract: This is a case report about Porphyria cutanea tarda (PCT) and its relationship with the infection caused by the human immunodeficiency virus (HIV). Cutaneous porphyria is an illness caused by enzymatic modification that results in partial deficiency of uroporphyrinogen decarboxylase (Urod), whi...
As porfirias são doenças raras que decorrem de deficiência enzimática em uma das oito enzimas que compõem a cadeia de biossíntese do heme e possuem manifestações clínicas variadas. Na maior parte das vezes, são distúrbios hereditários embora existam formas adquiridas. Apresentam ampla intera...
Desde a descoberta do vírus da hepatite C (VHC), em 1989, a hepatite C passou a ganhar especial relevância entre as causas de doença hepática crônica no mundo. Estima-se que aproximadamente 3% da população mundial estejam infectados pelo vírus da hepatite C, o que representa cerca de 170 milhões...
