Results: 12

Microemulsions Improve Topical Protoporphyrin IX (PpIX) Delivery for Photodynamic Therapy of Skin Cancer

Abstract We report here microemulsions (MEs) for topical delivery of protoporphyrin IX (PpIX) for Photodynamic Therapy (PDT) of skin cancers. Selected MEs consisting of Oil/Water (O/W) bicontinuous (BC) and Water/Oil (W/O) preparations were characterized as to pH, nanometric size, zeta potential, drug co...

Evaluación biológica de la exposición laboral al plomo
Biological assessment of the work-related exposure to lead

Introducción: El plomo, por su amplio uso causa una gran contaminación ambiental y problemas de salud en muchas partes del mundo. La Organización Mundial de la Salud incluyó el plomo dentro de una lista de diez productos químicos causantes de graves efectos sobre la salud. Objetivo: Evaluar los ni...

Evaluation of cell damage and modulation of cytokines TNF-α, IL-6 and IL-10 in macrophages exposed to PpIX-mediated photodynamic therapy

Braz. j. biol; 80 (3), 2020
Abstract Little is known regarding whether photodynamic therapy (PDT)-induced cell death can substantially compromise macrophages (MΦ), which are important cells in PDT-induced immune responses. Here, parameters of PDT-mediated MΦ cytotoxicity and cytokine production in response to protoporphyr...

5-Aminolevulinic acid photoactivated over planktonic and biofilm forms of Enterococcus faecalis as a pharmacological therapy alternative

The purpose of the study was to evaluate the antibacterial effect of protoporphyrin IX (PpIX) generated by the exogenous administration of 5-aminolevulinic acid or δ-ALA and activated with an argon laser over a planktonic and biofilm of Enterococcus faecalis (E. faecalis) as a pharmacological therapy al...

Iron deficiency, still a rarity in children with sickle cell anemia in Ile-Ife, Nigeria

ABSTRACT In this study, children with sickle cell anemia were evaluated for iron deficiency. Serum ferritin and free erythrocyte protoporphyrin free erythrocyte protoporphyrin (FEP) levels, mean corpuscular volume mean corpuscular volume (MCV) and mean corpuscular hemoglobin mean corpuscular hemoglobin (...

Photodynamic action of protoporphyrin IX derivatives on Trichophyton rubrum

An. bras. dermatol; 91 (2), 2016
Abstract: BACKGROUND: Dermatophytes are filamentous keratinophilic fungi. Trichophyton rubrum is a prevalent infectious agent in tineas and other skin diseases. Drug therapy is considered to be limited in the treatment of such infections, mainly due to low accessibility of the drug to the tissue attacke...

Ferritina sérica y protoporfirina eritrocitaria como indicadores de deficiencia de hierro en niños lactantes
Serum ferritin and erythrocyte protoporphyrin as iron deficiency indicators in infants

A nueve niños con anemia por deficiencia de hierro se les determinó el índice protoporfina eritrocitaria/hemoglobina (PPE:Hb) y los niveles de ferritina sérica antes, a los 15 y a los 30 días de administración de 2 mg de hierro/kg de peso/ día. Todos presentaron niveles anormales altos de protopor...

Intoxicaçäo por chumbo e cádmio em trabalhadores de oficinas para reforma de baterias em Salvador, Brasil
Lead and cadmium poisoning among workers of establishments for repair of batteries in Salvador, Brazil

Rev. saúde pública; 19 (5), 1985
Realizou-se estudo de tipo transversal sobre intoxicaçäo por chumbo e cádmio em trabalhadores no setor de reforma de baterias para veículos automotores. Foram estudados 39 trabalhadores procedentes de 19 estabelecimentos de pequeno porte, existentes na zona urbana de Salvador, Ba (Brasil). As condiç...

Determinacion de erytrocyte protoporphyrin asociado al zinco y otros valores hematologicos en donadores del banco de sangre del Hospital San Juan de Dios
Determination of erythrocyte protoporphyrin associated with zinc and other hematologic values in blood bank donors of the Hospital San Juan de Dios

La determinacion de protoporfirina eritrocitica unida a zinc (PE-Zn) constituye un metodo rapido, seguro, sensible y barato que permite detectar deficiencias latentes de hierro (Fe), anemia por deficiencia de este metal e intoxicaciones por plomo (Pb) Con el fin de obtener valores de referencia de hierro...