The therapeutic approaches for Type 2 Diabetes Mellitus rely most on the usage of oral hypoglycaemic drugs. These drugs have adverse side effects and hence alternative medicines are continuously explored. The present study intends to investigate the antidiabetic potential of the flavonoids present in Gra...
ALENCAR, DANIEL B DE;
DINIZ, JAÉCIO C;
ROCHA, SIMONE A S;
PIRES-CAVALCANTE, KELMA M S;
LIMA, REBECA L DE;
SOUSA, KAROLINA C DE;
FREITAS, JEFFERSON O;
BEZERRA, RAYSSA M;
BARACHO, BÁRBARA M;
SAMPAIO, ALEXANDRE H;
VIANA, FRANCISCO A;
SAKER-SAMPAIO, SILVANA.
ABSTRACT This study evaluated the chemical composition and antioxidant activity of fatty acids from the marine red algae Pterocladiella capillacea (S. G. Gmelin) Santelices & Hommersand 1997 and Osmundaria obtusiloba (C. Agardh) R. E. Norris 1991. The gas chromatography mass spectrometry (GC-MS) iden...
Análisis de Varianza,
Antioxidantes/análisis,
Antioxidantes/química,
FMN Reductasa/análisis,
Ácidos Grasos/análisis,
Ácidos Grasos/química,
Depuradores de Radicales Libres/análisis,
Cromatografía de Gases y Espectrometría de Masas,
Valores de Referencia,
Rhodophyta/química,
beta Caroteno/análisis
ABSTRACT Gracilariopsis lemaneiformis is a type of red alga that contains seaweed polysaccharide agar. In this study, a novel non-agar seaweed polysaccharide fraction named GCP (short of crude polysaccharide obtained from Gracilariopsis lemaneiformis) was isolated from Gracilariopsis lemaneiformis. Struc...
Proliferación Celular/efectos de los fármacos,
Cromatografía Líquida de Alta Presión,
Ensayo de Inmunoadsorción Enzimática,
Linfocitos/efectos de los fármacos,
Espectroscopía de Resonancia Magnética,
Microscopía Electrónica de Rastreo,
Estructura Molecular,
Peso Molecular,
Ácido Peryódico/química,
Polisacáridos/química,
Polisacáridos/aislamiento & purificación,
Valores de Referencia,
Rhodophyta/química,
Algas Marinas/química,
Espectroscopía Infrarroja por Transformada de Fourier
This study aimed to investigate the EEAm effect in mice models of nociception, inflammation and in behavioral tests evaluating the central nervous system. EEAm had inhibitory effects in the following tests: acetic acid-induced writhing (78%); formalin (62% - inflammatory phase); open field (46%). EEAm in...
A. muscoides (Rhodophyta) has three polysulfated fractions (-1, -2 and Am-3). Am-2 displayed anti -inflammation and serpin-independent anticoagulation effects; however, no effect of oligomers on thrombin-generation (TG) has been demonstrated. This study employed mild-acid hydrolysis to obtain low-molecul...
A natureza e diversidade das estruturas químicas com atividade farmacológica que se tem encontrado nos organismos marinhos justificam a busca por novos compostos que são de interesse nas mais diversas áreas de aplicação. As espécies de macroalgas vermelhas, em especial Laurencia spp., merecem dest...
Bioprospección/métodos,
25873/análisis,
Algas Marinas/metabolismo,
Citotoxinas,
Esfingosina,
Terpenos,
Productos Biológicos/administración & dosificación,
Código de Barras del ADN Taxonómico/22074,
Antioxidantes,
Rhodophyta/metabolismo,
Funciones de Verosimilitud
Muitas drogas terapêuticas produzidas pela indústria farmacêutica são estruturas químicas isoladas de organismos encontrados na natureza ou moléculas baseadas nelas. Podem ser incluídas nesse grupo drogas isoladas de organismos marinhos, como corais, esponjas e algas marinhas, conhecidos como prod...
(au)INTRODUCCIÓN: la terapia antiviral frente a las infecciones provocadas por virus influenza se basa en empleo de inhibidores de las proteínas M2 y neuraminidasa (NA). Sin embargo, la emergencia de cepas estacionales resistentes a ambos grupos de fármacos motiva la búsqueda de nuevos fármacos anti...
Background Enteric red mouth disease and Saprolegniasis, which are caused by the bacteria Yersinia ruckeri and the oomycete Saprolegnia parasitica, respectively, are important illnesses that affect salmonid farming. Sanitary problems in farms are addressed by the prevention of disease outbreaks or by the...
Rhodophyta/química,
Extractos Vegetales/farmacología,
Antiinfecciosos/farmacología,
Salmonidae,
Enfermedades de los Peces,
Cloruro de Metileno/farmacología,
Yersinia ruckeri/efectos de los fármacos,
Saprolegnia/efectos de los fármacos,
Cromatografía de Gases y Espectrometría de Masas,
Recuento de Colonia Microbiana,
Algas Marinas
The knowledge of the biodiversity of Gorgona, a continental island in Colombia, is very limited in the case of algae. We present an updated list of the benthic marine algae of Gorgona Island, associated with different marine environments and type of substrates, such as coral reefs, rocks, and soft bottom...
