El ácido valproico (VPA) es un fármaco antiepiléptico teratógenico que, al ser administrado durante etapas tempranas del embarazo, puede producir alteraciones en el desarrollo embriofetal, las que se manifiestan tanto a nivel del sistema nervioso como del testículo. No obstante, se ha reportado que ...
The effects of systemic insulin administration at different concentrations on the testicular tissue of diabetic adult rats, induced by streptozotocin, are evaluated by the morphological analysis of spermatogenic process. Twenty-four adult male rats were divided into 1) Control Group: they received citrat...
Miranda, Carla Maria Figueiredo de Carvalho;
Leonel, Luciano César Pereira Campos;
Koga, Bruna Andrade Aguiar;
Anunciação, Adriana Raquel de Almeida da;
Mario, Lara Carolina;
Favaron, Phelipe Oliveira;
Martins, Daniele dos Santos;
Vásquez, Bélgica;
Conei, Daniel;
Miglino, Maria Angélica;
Sol, Mariano del.
SUMMARY: The rabbit is considered an ideal animal model for studies that describe abnormalities in the testicles due to the similar morphogenetic mechanisms of sexual development and diseases commonly found in humans. The aim of this study was to determine the male sexual differentiation of the New Zeala...
SUMMARY: The aim of this study is to investigate the effects of Protocatechuic acid and Corchorus olitorius on streptozotocin (STZ) induced diabetic rat testis tissue. Randomly selected Wistar Albino rats were divided into five groups as; Diabetes Mellitus, Diabetes Mellitus treated with Corchorus Olitor...
This study aimed to evaluate the effect of immunocastration on the scrotal circumference, as well as in the macroscopic and microscopic testicular features in Nellore bulls bred under a semi-confining system for 91 days. Sixty animals were divided into two groups: 30 intact animals (non-vaccinated) and 3...
Hypoxia hypobaric (HH) can cause alterations at testicular level, with temperature increase, intrascrotal alteration and deterioration of spermatogenesis. Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ketoprofen have anti-angiogenic properties, and can decrease testicular abnormalities. The objec...
Cetoprofeno/farmacología,
Cetoprofeno/administración & dosificación,
Hipoxia/fisiopatología,
Testículo/efectos de los fármacos,
Testículo/lesiones,
Espermatogénesis/efectos de los fármacos,
Antiinflamatorios no Esteroideos/farmacología,
Antiinflamatorios no Esteroideos/administración & dosificación,
Hematócrito,
Reticulocitos/efectos de los fármacos,
Túbulos Seminíferos/efectos de los fármacos,
Neovascularización Patológica
Abstract Purpose: To quantify, through stereological and morphometric analysis, spermatogenesis in rats undergoing the natural aging process. Methods: Seventy-two male Wistar rats were divided into 6 equal groups according to age at the time of killing: 3, 6, 9, 12, 18, and 24 months. All the rats were...
Flaxseed is considered a functional food with several health benefits. However, because of its high phytoestrogen content, flaxseed influences hormone metabolism and affects the gonadal biomorphology. In this study, computerized histomorphometry was used to evaluate seminiferous and epididymal tubules, c...
Abstract Purpose: To investigate the effect of buserelin on gonadal structure and function in adult male rats. Methods: Twenty-four adult Wistar male rats were divided into three groups: two treated groups and controls. The first and second treated groups received 300 (low dose) and 500 (high dose) µ...
Apoptosis/efectos de los fármacos,
Buserelina/administración & dosificación,
Fármacos para la Fertilidad Masculina/administración & dosificación,
Túbulos Seminíferos/efectos de los fármacos,
Buserelina/efectos adversos,
Fármacos para la Fertilidad Masculina/efectos adversos,
Etiquetado Corte-Fin in Situ,
Modelos Animales,
Ratas Wistar,
Túbulos Seminíferos/patología,
Testículo/anatomía & histología,
Testículo/efectos de los fármacos,
Testosterona/sangre
Foram utilizadas as gônadas e vias espermáticas de cinco animais machos, adultos em fase reprodutiva, da espécie Metachirus nudicaudatus Geoffroy 1803, única espécie do gênero, para descrever a morfologia do escroto, do testículo e das vias espermáticas. O Metachirus possui escroto pré-peniano e...
