Purpose: This study evaluated the DNA damage caused by repeated doses of xylazine-ketamine and medetomidine-ketamine anesthesia in the liver and kidneys. Methods: In this study, 60 rats were used. The rats were divided into group 1 (xylazine-ketamine), and group 2 (medetomidine-ketamine), and these anes...
ABSTRACT Purpose: To describe a new anesthetic protocol medullary and nerve roots access and in Rattus norvegicus. Methods: Seventy female Wistar rats (n=70) were used. The animals were randomly divided into two laminectomy groups: cervical (n=40) and thoracic (n=30). In cervical group, a right posteri...
ABSTRACT Purpose: To compare the penile histoarchitecture of rats euthanized with isoflurane or with ketamine and xylazine. Methods: Fourteen male rats were divided into two groups: ISO, with animals euthanized with isoflurane; and K+X, with animals euthanized with ketamine (150 mg/kg) associated with ...
The mixture of ketamine and xylazine is widely used for the auditory brainstem response (ABR) measurement. Esketamine is twice as potent as ketamine. Our objective was to assess the influence of esketamine in mice undergoing cochlear function measurement including ABR and distortion product otoacoustic e...
Blocking of the growth plate (GP) using plates with screws (tension band plating) is a modern method used to correct deformities and moderate leg length discrepancy in growing children. Determining the duration of temporary bilateral blocking without the occurrence of irreversible changes of GP is of par...
Conejos/cirugía,
Deformidades Congénitas de las Extremidades/terapia,
Desarrollo Infantil,
Fémur/crecimiento & desarrollo,
Fémur/citología,
Fémur/diagnóstico por imagen,
Fenobarbital/administración & dosificación,
Fijadores/análisis,
Ketamina/administración & dosificación,
Pierna/anomalías,
Placa de Crecimiento/crecimiento & desarrollo,
Placa de Crecimiento/anomalías,
Placas Óseas,
Reducción del Daño,
Xilazina/administración & dosificación,
Cefazolina/administración & dosificación
Jamal, Muhammad Ameen;
Ahmed, Arslan Mahmood;
Tahir, Muhammad;
Ashraf, Muhammad;
Sattar, Abdul;
Ghafoor, Aamir;
Munir, Shahzad;
Ahmed, Irfan;
Hussain, Mubashir;
Riaz, Amjad.
Anesthetics are an indispensable prerequisite for surgical intervention and pharmacological animal studies. The objective of present study was to optimize the dose of ketamine (K) and xylazine (X) along with atropine sulfate (A) in order to achieve surgical tolerance in BALB/c mice. Several doses of keta...
ABSTRACT Objectives: To evaluate protective effects of darbepoetin and tadalafil against ischemia-reperfusion injury in ipsilateral and contralateral testicle. Materials and Methods: Thirty 3-month-old adult male Wistar-Albino rats were randomly divided into 5 groups (A-E). Sham operation was performed...
Darbepoetina alfa/administración & dosificación,
Modelos Animales de Enfermedad,
Inmunohistoquímica,
Ketamina/administración & dosificación,
Distribución Aleatoria,
Ratas Wistar,
Daño por Reperfusión/tratamiento farmacológico,
Torsión del Cordón Espermático/tratamiento farmacológico,
Torsión del Cordón Espermático/patología,
Tadalafilo/administración & dosificación,
Vasodilatadores/administración & dosificación,
Xilazina/administración & dosificación
Um exemplar de rato-do-bambu (Dactylomys dactylinus) subadulto saudável do sexo feminino, de vida livre, com massa corporal de 0,32 kg, recebeu por via intramuscular, em uma única injeção, doses de tiletamina, zolazepam, xilazina e atropina calculadas por meio de extrapolação alométrica interespec...
Onze ouriços-cacheiros (Sphiggurus spp.) foram contidos farmacologicamente para realização de exames médicos e procedimentos de manejo. Utilizaram-se, para tal finalidade, xilazina (dose média de 2,32 mg/kg) e cetamina (dose média de 29,66 mg/kg), combinadas na mesma seringa, administradas no terç...
Avaliaram-se os efeitos das injeçöes intravenosa (iv) de amitraz (0,1mg/kg) e xilazina (1mg/kg), em cavalos, sobre a atividade cardíaca, freqüência respiratória, atividade motora intestinal, temperatura retal, sudorese e freqüência de apreensäo de alimentos. O amitraz causou diminuiçäo signifi...
