The objective of this study is to examine the antidepressant and antioxidant effects of thymoquinone (TQ) on reserpine-induced depression, and to investigate the antidepressant and antioxidant activity of combined treatment of TQ+citalopram. In total, 36 male Wistar rats were randomly divided into 6 grou...
ABSTRACT Objective This scoping review aimed to map evidence on açai supplementation combined with exercise in animal and/or human experimental studies. Methods The search considered six electronic databases and screening of relevant references. The selection process and data extraction were performed...
Abstract Up to today, there is no specific treatment against SARS-CoV-2 / COVID-19 infection; there the necessity to search for alternatives that help patients with COVID-19. The objective of this study was to review the use of ozone therapy as adjunct treatment for SARS-CoV-2 / COVID-19 infection, highl...
Yildirim, Yasar;
Bahadir, Veysi;
Aydin, Emre;
Aydin, Fatma Yilmaz;
Yilmaz, Zülfükar;
Ketani, Aydin;
Kaplan, Ibrahim;
Tuncer, Mehmet Cudi;
Kadiroglu, Ali Kemal;
Yilmaz, Mehmet Emin.
SUMMARY: N-Acetylcysteine (NAC) is used for contrast induced acut kidney injury (CI-AKI) prophylaxis because of its antioxidant effects. Paricalcitol, which has reno-protective effects, is likely to provide a more effective prophylaxis when added to NAC treatment. The study was designed based on this hyp...
Lesión Renal Aguda/prevención & control,
Lesión Renal Aguda/inducido químicamente,
Medios de Contraste/efectos adversos,
Ergocalciferoles/administración & dosificación,
Ergocalciferoles/farmacología,
Acetilcisteína/administración & dosificación,
Acetilcisteína/farmacología,
Antioxidantes/administración & dosificación,
Antioxidantes/farmacología,
Estrés Oxidativo/efectos de los fármacos,
Ratas Wistar
SUMMARY: Diabetes and hypertension account for the majority of chronic kidney injury cases that can lead to renal failure. The link between the leukocytes common antigen (CD45) and diabetic kidney disease (DKD) with and without metformin incorporation in an animal model has not been investigated before. ...
Diabetes Mellitus,
Metformina/administración & dosificación,
Metformina/uso terapéutico,
Hipoglucemiantes/administración & dosificación,
Hipoglucemiantes/uso terapéutico,
Lesión Renal Aguda/prevención & control,
Inflamación,
Modelos Animales de Enfermedad,
Biomarcadores,
Estrés Oxidativo/efectos de los fármacos,
Antígenos Comunes de Leucocito,
Riñón/efectos de los fármacos
Abstract The aim of the present study is to investigate the cardioprotective effects of 18β-glycyrrhetinic acid (18β -GA) against oxidative and histological damage caused by global cerebral ischemia/ reperfusion (I/R) in C57BL/J6 mice. All male mice (n:40) were randomly divided into four groups: (1) s...
Purpose:
This study investigated the effects of oral administration of Clostridium butyricum (C. butyricum) on inflammation, oxidative stress, and gut flora in rats with hepatic ischemia reperfusion injury (HIRI).
Methods:
The rats from C. butyricum group were given C. butyricum for 5 days. Then, hepati...
Abstract Ischemia/reperfusion (IR) injury leads to overproduction of Reactive Oxygen Species (ROS), and disrupts membrane potential that contributes to cell death. The aim of this study was to determine if naringin (NAR), trimetazidine (TMZ) or their combination, protect the kidney mitochondrial from IR ...
Abstract The aim of this study was to assess the effects of methanol extract of G. verum on redox status of isolated heart of spontaneously hypertensive rats after ischemia. Twenty-four Wistar albino rats were divided into three groups: untreated control rats and rats that received 125 and 250 mg/kg G. v...
Abstract Acrylamide is a neurotoxic compound. Moreover, anakinra is an interleukin-1 (IL-1) receptor antagonist used in rheumatoid arthritis treatment. This study investigated the effect of anakinra on acrylamide-related neuropathy and neuropathic pain. Acrylamide exposure caused a significant decrease ...
