ABSTRACT Introduction: primary liver sarcoma is a rare type of tumor, more common in children. Among adults, it represents a spectrum of neoplasms with reserved prognosis. There is no consensus on the treatment of choice of these lesions, justifying a systematic review of the literature on treatment op...
SUMMARY Hepatocellular carcinoma in patients with hepatitis C in the absence of cirrhosis is uncommon. We demonstrate the importance of morphofunctional magnetic resonance imaging (MRI) with a hepatospecific contrast agent by describing an asymptomatic female patient with HCV, who presented with a nodule...
This study aimed to explore the prognostic role of dipeptidyl peptidase 4 (DPP4) expression in hepatocellular carcinoma (HCC). DPP4 expression was measured in formalin-fixed paraffin-embedded specimens that were gathered from 327 HCC patients. Immunohistochemistry analyses were utilized to examine DPP4 e...
Biomarcadores de Tumor,
Carcinoma Hepatocelular/genética,
Carcinoma Hepatocelular/metabolismo,
Carcinoma Hepatocelular/mortalidad,
Dipeptidil Peptidasa 4/metabolismo,
Estudios de Seguimiento,
Inmunohistoquímica,
Neoplasias Hepáticas/genética,
Neoplasias Hepáticas/metabolismo,
Neoplasias Hepáticas/mortalidad,
Recurrencia Local de Neoplasia,
Pronóstico,
Ensayos Antitumor por Modelo de Xenoinjerto
Abstract Long-chain non-encoded RNAs (lncRNAs) are important in many life activities and can participate in the occurrence of hepatocellular carcinoma (HCC). Moreover, lncRNAs can be used as basis for developing new strategies to hinder liver cancer. To investigate the utility of lncRNAs in HCC as potent...
Chagas, Aline Lopes;
da Fonseca, Leonardo Gomes;
Coelho, Fabricio Ferreira;
da Cunha Saud, Lisa Rodrigues;
Abadala, Edson;
Andraus, Wellington;
Fiore, Lucas;
Moreira, Airton Mota;
Menezes, Marcos Roberto;
Carnevale, Francisco César;
Tani, Claudia Megumi;
Alencar, Regiane S S M;
DAlbuquerque, Luiz Augusto Carneiro;
Herman, Paulo;
Carrilho, Flair José.
More than 18 million people in 188 countries have been diagnosed as having coronavirus disease (COVID-19), and COVID-19 has been responsible for more than 600,000 deaths worldwide. Brazil is now the second most affected country globally. Faced with this scenario, various public health measures and change...
Betacoronavirus,
Brasil/epidemiología,
COVID-19,
Carcinoma Hepatocelular/epidemiología,
Carcinoma Hepatocelular/terapia,
Consenso,
Infecciones por Coronavirus,
Neoplasias Hepáticas/epidemiología,
Neoplasias Hepáticas/terapia,
Pandemias,
Neumonía Viral,
SARS-CoV-2
Hepatocellular carcinoma (HCC) is one of the most common primary malignant tumors of the liver worldwide. Liver resection and transplantation are currently the only effective treatments; however, recurrence and metastasis rates are still high. Previous studies have shown that the epithelial-mesenchymal t...
Antineoplásicos/farmacología,
Antineoplásicos/uso terapéutico,
Carcinoma Hepatocelular/tratamiento farmacológico,
Carcinoma Hepatocelular/genética,
Proliferación Celular/efectos de los fármacos,
Proliferación Celular/genética,
Modelos Animales de Enfermedad,
Ensayos de Selección de Medicamentos Antitumorales,
Transición Epitelial-Mesenquimal/efectos de los fármacos,
Isoflavonas/farmacología,
Isoflavonas/uso terapéutico,
Neoplasias Hepáticas/tratamiento farmacológico,
Neoplasias Hepáticas/genética,
MicroARNs/genética,
Invasividad Neoplásica,
Fosfohidrolasa PTEN/genética,
Pirroles
ABSTRACT Background: There have been an increasing number of articles that demonstrate the potential benefits of minimally invasive liver surgery in recent years. Most of the available evidence, however, comes from retrospective observational studies susceptible to bias, especially selection bias. In ...
ABSTRACT Background: Majority of patients with large size HCC (>10 cm) are not offered surgery as per Barcelona Clinic Liver Cancer (BCLC) criteria and hence, their outcomes are not well studied, especially from India, owing to a lower incidence. Aim: To analyze outcomes of surgery for large HCCs....
ABSTRACT Background: Laparoscopic liver resection is performed worldwide. Hemorrhage is a major complication and bleeding control during hepatotomy is an important concern. Pringle maneuver remains the standard inflow occlusion technique. Aim: Describe an extracorporeal, efficient, fast, cheap and re...
Carvalho, Vithor de Oliveira;
Galastri, Francisco Leonardo;
Affonso, Breno Boueri;
Falsarella, Priscila Mina;
Valle, Leonardo Guedes Moreira;
Ferraz-Neto, Ben-Hur;
Rezende, Marcelo Bruno de;
Motta-Leal-Filho, Joaquim Maurício da;
Garcia, Rodrigo Gobbo;
Nasser, Felipe.
ABSTRACT Transarterial radioembolization (TARE) with yttrium-90 microspheres is a palliative locoregional treatment, minimally invasive for liver tumors. The neoadjuvant aim of this treatment is still controversial, however, selected cases with lesions initially considered unresectable have been enframed...
