Results: 108

Beneficio de la quimioterapia adyuvante en pacientes con cáncer de colon: cohorte retrospectiva de un hospital clínico universitario

Rev. méd. Chile; 144 (2), 2016
Background: Multiple clinical trials have demonstrated the benefits of adjuvant 5-fluorouracil-based chemotherapy for patients with resectable colon cancer (CC), especially in stage III. Aim: To describe the clinical characteristics of a cohort of CC patients treated at a single university hospital in Ch...

Pharmacovigilance of patients with multiple myeloma being treated with bortezomib and/or thalidomide

Braz. j. med. biol. res; 49 (6), 2016
In order to evaluate the main adverse effects of drug protocols using bortezomib and/or thalidomide for the treatment of multiple myeloma, we conducted a prospective study. Data were collected through interviews, clinical observation, and from hospital records. A total of 59 patients were included. There...

Dermatite flagelada induzida por bleomicina: relato de caso

Cogit. Enferm. (Online); 20 (2), 2015
A Dermatite Flagelada consiste de uma hiperpigmentação cutânea de aspecto flagelado, tendo como causa específica a bleomicina. A bleomicina é um agente quimioterápico usado no tratamento de diferentes neoplasias. O objetivo deste relato é descrever o caso de uma paciente de 31 anos de idade, em t...

Evaluación del efecto del tratamiento combinado de mangiferina con cisplatino y 5-fluorouracilo en células CT26. WT y CHO-K1
Evaluation of combination treatment effect of mangiferin with cisplatin and 5-fluorouracil in CT26. WT and CKO-K1 cells

Rev. cuba. farm; 48 (4), 2014
INTRODUCCIÓN: la mangiferina posee diferentes propiedades farmacológicas, y otras están por ser investigadas, tal como su actividad antitumoral como agente adyuvante a la quimioterapia antineoplásica convencional en la terapia combinada. OBJETIVO: evaluar el efecto antiproliferativo de la mangiferina...

Clinical and economic aspects of the use of rituximab in non-Hodgkin's lymphoma

Braz. j. pharm. sci; 50 (3), 2014
Non-Hodgkin's lymphoma (NHL) consists of a group of neoplasias involving mainly B cells and represents 90% of all lymphomas. The current available therapy is based on chemotherapy associated with the monoclonal antibody rituximab (Mab Thera(r)), which targets the CD20 protein, present in over 80% of NHL ...

High-dose tamoxifen plus ifosfamide and anthracycline in a patient with angiosarcoma of the breast

West Indian med. j; 62 (7), 2013
Although breast cancer is, unfortunately, not uncommon in women, a mere 0.04% of malignant breast tumours are primary angiosarcomas. Chemotherapy is advocated for treatment of breast angiosarcomas; however, no guidelines exist regarding optimal chemotherapeutics or protocols. Presently, the prognosis for...

Primary bone marrow B-cell non-hodgkin's lymphoma successfully treated with R-CHOP

West Indian med. j; 62 (1), 2013
Primary isolated bone marrow disease as a presenting feature of lymphoma is very rare. We describe the case of a Chinese with isolated bone marrow small B-cell lymphoma as a first manifestation. A 55-year old woman was admitted to our hospital with fever. Her peripheral blood smear and laboratory finding...

Qualidade de vida de idosos em tratamento quimioterápico atendidos no ambulatório de oncologia do Instituto de Medicina Integral prof. Fernando Figueira - IMIP, Recife, Brasil

Cenário: para alguns grupos de pacientes, a qualidade de vida relacionada à saúde (QVRS) tem sido o objetivo primordial do tratamento oncológico, se sobrepondo inclusive ao aumento de sobrevida. Isso se torna particularmente importante em idosos com câncer, pois o tratamento, seja pela toxidade da d...